SIADH vs Psychogenic Polydipsia

Slides:

Advertisements

Similar presentations

Regulation of Extracellular Fluid Osmolarity and Sodium Concentration

Advertisements

LPN-C Unit Three Fluids and Electrolytes. Why are fluids and electrolytes important for the nurse to understand? Fluids and electrolytes are essential.

Syndrome of Inappropriate Antidiuretic Hormone (SIADH) Daniel Stairs, CRNA, MSN, MBA Excela Health School of Anesthesia.

Physiology of Hyponatremia Hyponatremia results from either the excessive intake or inability to excrete free water. Water intake  dilutional fall in.

RENAL REGULATION OF BODY FLUID Dr. Eman El Eter. What is the impact of the following on your body fluid volume and osmolarity?  What happens when you.

Diabetes Insipidus Ovidiu Galescu MD. Definition  Diabetes insipidus (DI) is an uncommon condition that occurs when the kidneys are unable to conserve.

Hormone Regulation of Urine Formation

Volume of Urine GFR ~ L/d Urine, ~ 0.5 – 15 L/d.

© 2006 McGraw-Hill Higher Education. All rights reserved. Chapter 8 Medication for Mental Disorders.

Reabsorption and Secretion. Learning Objectives Understand how fluid flow from the tubular lumen to the peritubular capillaries. Know how the reabsorption.

SIADH, DI, Cerebral Salt Wasting

By Dr. Adrienne Hicks.  Cardiology  Pulmonology  Renal  Gastrointestinal  Endocrine  Reproductive  Neurology  Musculoskeletal  Psychiatry  Pediatrics.

Overview of the Maintenance of Water and Ions Kidneys Baroreceptors Osmoreceptors.

URINARY SYSTEM FUNCTION.

Vertebrate kidney structure and function ap biology chapter 44.

Adult Medical-Surgical Nursing Endocrine Module: Disorders of the Posterior Pituitary Gland.

Physiology of the Kidney Urine Formation. Filtration  Occurs in the glomerulus  Renal artery branches off into tiny capillaries upon entering the kidney.

Causes 1. Infarction : Sheehan’s syndrome 2. Iatrogenic : Radiation, urgery 3. Invasive : Large pituitary tumors CRANIOPHARYNGIOMA 4. Infiltration : Sarcoidosis,

Urinary System. Urinary System Function The function of the urinary system is to help maintain the appropriate balance of water and solutes in the bodies.

Driving Force of Filtration n The filtration across membranes is driven by the net filtration pressure n The net filtration pressure = net hydrostatic.

Adalyn Almora Questions 3 and 4

Disorders of ADH secretion Dr. Eman El Eter. Deficiency: Diabetes Insipidus. Excess secretion: Syndrome of inappropriate ADH secretion (SIADH)

Biology 212 Anatomy & Physiology I Dr. Thompson Renal.

CHAPTER 15 Urinary System. Kidney Functional Units No direct exchange – substances diffuse through interstitial fluid Renal artery/vein: kidney blood.

Human Anatomy and Physiology Renal function. Functions Regulation of water and electrolytes Maintain plasma volume Acid-base balance Eliminate metabolic.

Urinary System – Physiology. The normal healthy adult produces 1-2 liters of urine a day. Filtration: The movement of fluid across the filtration membrane.

The Pathway of ADH The Effect of SIADH Larry Li

Blood Pressure Regulation- Background info ► Water will go where there are high concentrations of Salt ► Increase in water = increase in volume ► Increase.

Diabetes Insipidus Dr. Khalid Alregaiey.

Diabetes Insipidus Definition : It is a condition characterized by excessive thirst and polyurea secondary to deficiency of vasopressin (antidiuretic hormone.

Daniel R. Kapusta, Ph.D. Department of Pharmacology, LSUHSC MEB Rm ; Urine Concentration and Dilution Regulation of Sodium.

Water Balance: Hypo- and Hypernatremia Vivek Bhalla, MD Division of Nephrology Stanford University School of Medicine September 14th, 2015.

Regulation of Extracellular Fluid Osmolarity and Sodium Concentration

Regulation of Extracellular Fluid Osmolarity and Sodium Concentration

Hormonal Control of Osmoregulation & Excretion WALT That water concentrations are regulated by a hormone called ADH That ADH effects the permeability.

WEM1 Lab diagnostics MK, JSC 2015/2016. Sodium deficit Postoperatively a 70-kg patient has a serum sodium value of 120 mEq/L (120 mmol/L) to increase.

Posterior pituitary hormones: The posterior pituitary hormones, vasopressin (ADH) and oxytocin. These hormones are synthesized in the hypothalamus and.

Water balance in mammals Water balance in mammals is controlled by the kidneys, hypothalamus and the adrenal glands It involves 3 main hormones: Anti-diuretic.

SIADH, Cerebral Salt Wasting

Diabetes Insipidus & ADH hypersecretion Dr. Abdulmoein Eid Al-Agha Assistant Professor & Consultant Pediatric Endocrinologist, King AbdulAziz University.

3. Compute for the plasma osmolality and the effective plasma osmolality. What is the importance of computing for such?

Date of download: 6/6/2016 From: Psychopharmacologic Treatment Strategies for Depression, Bipolar Disorder, and Schizophrenia Ann Intern Med. 2001;134(1):47-60.

Renal regulation of body fluid

Countercurrent Mechanism

Diabetes Insipidus and SIADH Charnelle Lee RN, MSN.

Diabetes A metabolism disorder that causes excessive amounts of urine production.

Severe Hypernatremia Following Treatment of the Syndrome of Inappropriate Antidiuretic Hormone Secretion Khaldoun Soudan, MD, Wajeh Qunibi, MD The American.

Posterior pituitary Dr. Hana Alzamil

EXCRETORY SYSTEM PP

Urine Formation Is a result of three processes which help to regulate the blood composition and volume Filtration Reabsorption Secretion Function of Nephron.

Figure 26.1 An introduction to the Urinary System

ADH and Osmoregulation

Urinary System Day 4.

Formation Of Concentrated Urine

I will understand how the volume of urine is regulated.

Tubular processing of the glomerular filtrate. The renal tubules process the glomerular filtrate by: Reabsorption: Transport of a substance from the tubular.

Kidneys and Homeostasis

به نام خالق زیبایی ها Hormone 2 Dr.Radmanesh.

Foundations of Anatomy and Physiology II

Excretory System Blood Pressure Hormones.

Antidiuretic hormone (ADH) Good example of Negative feedback loop

Is it cerebral or renal salt wasting?

Antidiuretic hormone (ADH) Good example of Negative feedback loop

Circulatory and Excretory Systems

Hormonal Control of Tubular Reabsorption HORMONES THAT REGULATE ABSORPTION EFFECTS Aldosterone ↑ NaCl,H2 O reabsorption, ↑ K+ secretion Angiotensin.

Low salt BM 2019 MMC.

(Top) A urine sodium concentration (UNa) of approximately 30 mEq/L is observed frequently in patients with hyponatremia secondary to syndrome of inappropriate.

Presentation transcript:

SIADH vs Psychogenic Polydipsia Tomm Caspi פנימית ב' ביה"ח תל-השומר

SIADH Inappropriate excess secretion of Anti-Diuretic Hormone even when plasma osmolarity is low (<275-280 mOsm/L) High urine osmolality (>100 mOsm/L)- implying ADH concentrated the urine in the collecting duct High urine Sodium- the force of reabsorption into the peritubular vessels is reduced Low Uric-Acid in the blood- reduced reabsorption.

Drugs that induce SIADH Vasopressin or desmopressin Chlorpropamide Oxytocin, high dose Vincristine Carbamazepine Nicotine Phenothiazines Cyclophosphamide Tricyclic antidepressants Monoamine oxidase inhibitors Serotonin reuptake inhibitors

Psychogenic Polydipsia SIADH Psychogenic Polydipsia ADH (0) Plasma osmolarity <275-280 mOsm/L Urine osmolality >100 mOsm/L 50 mOsm/L Urine Sodium levels > 20 meq/L < 10 meq/L Increased water intake Brian Dundas, Melissa Harris and Meera Narasimhan, Current Psychiatry Reports, 2007.