BP TECH BIOPOLYTECH Inc, , Pungseo-ri, Pungse-myun, Cheonan-city, Chungcheongnam-do, Korea TEL: 041) FAX: , Homepage: Human Health & Nutraceutical F Human Environment OR BioPolytech Inc., Aagaro-Oiligosaccharide

BIOPOLYTECH Inc,. BP TECH PRODUCT BULLETIN Product Name Introduction The Function Usage Packing Net 20kg Carton Box Human Health&Nutraceutical Agaro Oligosaccharide ITEMSPECIFICATIONREMARK AppearancePowder of White Particle Size 〈 100 mash Moisture(%) 〈 10 Residue on ignition(%)<1 pH3~51% solution Heavy metal(Pb) 〈 1 Wt ppm ICP Heavy metal(Hg) 〈 2 Wt ppm ICP Agaro oligosaccharide(%) 〉 70 Coliform groupNegative ■ SPECIFICATION , Pungseo-ri, Pungse-myun, Cheonan-city, Chungcheongnam-do, Korea TEL: FAX: , Homepage: As a polysaccharide, agar is a fan-shaped polysaccharide that has a basic structure of galactose and 3, 6-anhydrogalactose. Agarooligosaccharide is a functional substance for antioxidant activity, prevention and treatment of arthritis, anti-cancer activity, blood sugar-lowering activity, prevention of starch aging and whitening effect etc. 1. Antioxidant activity 2. Prevention and treatment of arthritis 3. Anti-cancer activity 4. Blood sugar-lowering activity 5. Prevention of starch aging 6. Whitening effect 1. Health foods 2. Food additives (preservatives) 3. Cosmetic materials

BP TECH BIOPOLYTECH Inc,. PRODUCT BULLETIN Fig. 1. Human Health & Nutraceutical Agarooligosaccharide ? , Pungseo-ri, Pungse-myun, Cheonan-city, Chungcheongnam-do, Korea TEL: FAX: , Homepage: Agar-Agar 그림 1. AgarobioseAgarotetraose Agarohexaose Agarooligosaccharide Hydrosis of a-1,3 bond 1. Agarooligosaccharide? As a polysaccharide, agar is a fan-shaped polysaccharide that has a basic structure of galactose and 3, 6-anhydrogalactose. Manufactured its molecular weight below 5,000 by decomposing agar, Agarooligosaccharide is, as shown in the drawing no. 1, a functional substance for antioxidant activity, prevention and treatment of arthritis and anti-cancer activity etc.

BP TECH BIOPOLYTECH Inc,. PRODUCT BULLETIN Human Health & Nutraceutical Function of Agarooligosaccharide? , Pungseo-ri, Pungse-myun, Cheonan-city, Chungcheongnam-do, Korea TEL: FAX: , Homepage: 1. Antioxidant activity Nitrogen monoxide (NO) is functioning to lower blood pressure, widen blood vessels and kill germs in the human body. If nitrogen dioxide (NO2) is over-existed in the body by the stimulus of stress and ultraviolet rays etc., then it is recognized as an active oxygen molecule to induce cell destruction, chronic renal failure, colitis caused by tumor, arthritis, cataract, glaucoma and cancer etc. So, in order nitrogen dioxide not to be over-produced, it is needed to take food to inhibit it to the normal level and function to antioxidant activity. It is discovered that this agarooligosaccharide inhibit the over-formation of nitrogen dioxide and maintain it to the normal level. [Applicable case] Production inhibitory effect of nitrogen dioxide by agarooligosaccharide If nitrogen oxide is produced excessively in the body, it promotes cartilage destruction by restraining the composition of cartilages like collagen and proteoglycan. In the case of animal experiment for the patient model with chronic joint rheumatism, it is found that when taken, incidence rate is significantly restrained and the treating effect is also proven. 2. Anti-arthritis effect

BP TECH BIOPOLYTECH Inc,. PRODUCT BULLETIN Human Health & Nutraceutical , Pungseo-ri, Pungse-myun, Cheonan-city, Chungcheongnam-do, Korea TEL: FAX: , Homepage: 3. Inhibition of cancer cells cancer cells proliferation proliferation It is proved that agarooligosaccharide induces apotosis activity on various cancer cells and inhibits the cancer cells proliferation. Function of Agarooligosaccharide? [Applicable case] Treating effect of arthritis by agarooligosaccharide [Applicable case]Inhibitory effect on cancer cells by agarooligosaccharide

BP TECH BIOPOLYTECH Inc,. PRODUCT BULLETIN Human Health & Nutraceutical , Pungseo-ri, Pungse-myun, Cheonan-city, Chungcheongnam-do, Korea TEL: FAX: , Homepage: Function of Agarooligosaccharide? It is very useful for the fundamental treatment of type 2 diabetes, obesity, prevention of type 2 diabetes and also health food, with high safety for human body and inhibitory activity of high blood sugar that is useful for prevention of type 2 diabetes. (The main patent no ) 4. Lowering agent of blood sugar In the Japanese pancake industry, they manufacture their pancake products with excellent keeping quality and feeling of texture by adding agrooligosaccharide 5. Prevention of starch aging As a result of inhibition experiment for melanin formation through mouse B16 melanoma cell, it is proved of inhibitory effect for melanin formation. (by a research report from Gifu, Japan in 2004) 6. Antibiotic function It increases the keeping quality of products by the activation of natural preservatives. 7. Whitening effect