Day DateReadingTopic T10/15no class – October Vacation Th10/17More plant development T10/22Ch. 8Mechanisms of morphogenesis Th10/24More morphogenesis T10/29Ch.

Slides:



Advertisements
Similar presentations
Drosophila melanogaster 2.5mm Movie. The Life Cycle 1-2 weeks 36hr 60 hr 12 hr.
Advertisements

Pattern formation in drosophila Katja Nowick TFome and Transcriptome Evolution
Drosophila – 2 lectures (½ – 1- ½ ) Cleavage View -gastrulation, organogen. frame metamorph. Once we know the embryo, meet the molecules Because this is.
The Genetic Basis of Development
Th10/2 Ch. 2Molecular development of Drosophila T10/7More molecular development of Drosophila Th10/9Ch. 7Plant development On Thursday, 10/9, Please bring.
Lecture 6 Anterior posterior axis formation-the posterior signal Anterior posterior axis formation-down the hierarchy.
9.17 Generalized model of Drosophila anterior-posterior pattern formation (Part 1)
MiRNA  miRNA ancient form of regulation.  Protection against viral pathogens  Quick regulation and turnover of mRNA.
Embryonic Development & Cell Differentiation. During embryonic development, a fertilized egg gives rise to many different cell types Cell types are organized.
Anterior-posterior patterning in Drosophila
BioSci 108 lecture 26 (Blumberg) page 1 © copyright Bruce Blumberg All rights reserved Bio /13/2000 Molecular Genetics of Pattern Formation.
Gradients, cascades, and signaling pathways
I can’t wait to grow up! Laugh now.
6 and 8 November, 2006 Chapter 18 Gene Regulation During Development.
Figure Homologous Pathways Specifying Neural Ectoderm in Protostomes (Drosophila) and Deuterostomes (Xenopus) D/V.
Drosophila dorsal/ventral axis detemination How are different tissue types specified at distinct positions on the embryonic dorsal- ventral axis?
Drosophila dorsal/ventral axis detemination
Drosophila melanogaster development How do Drosophila embryos develop? How can one use genetics to find genes that regulate embryo development?
Chapter 9 - Axis specification in Drosophila Drosophila genetics is the groundwork for _______________l genetics Cheap, easy to breed and maintain Drosophila.
BIO305 Developmental Biology Instructor: Dave Champlin show resources on web site I try to record and post lectures. They are posted for one week only.
Chapter 19 Cellular Mechanisms of Development
Developmental Biology
Day DateReadingTopic Th11/28no class – Thanksgiving Break T12/3Ch. 12more on Neurogenesis Th12/5Ch. 9 The Saga of the Germ Line T12/10more on Reproduction.
BIO305 Developmental Biology Instructor: Dave Champlin.
Day DateReadingTopic T 9/3 pp (Ch. 6) C. elegans, model systems, and molecular genetics Watch three Audio/Video handouts: 1A), 1B), and 1C Th9/5Ch.
Day DateReadingTopic T 9/2 pp (Ch. 6) C. elegans, model systems, and molecular genetics Watch three Audio/Video handouts: 1A), 1B), and 1C Th9/4Ch.
Day DateReadingTopic T 9/2 pp (Ch. 6) C. elegans, model systems, and molecular genetics Watch three Audio/Video handouts: 1A), 1B), and 1C Th9/4Ch.
Day DateReadingTopic Th11/28no class – Thanksgiving Break T12/3Ch. 12more on Neurogenesis Th12/5Ch. 9 The Saga of the Germ Line T12/10more on Reproduction.
Day DateReadingTopic T10/15no class – October Vacation Th10/17More plant development T10/22Ch. 8Mechanisms of morphogenesis Th10/24More morphogenesis.
Drosophila melanogaster
Day DateReadingTopic Th11/28no class – Thanksgiving Break T12/3Ch. 12more on Neurogenesis Th12/5Ch. 9 The Saga of the Germ Line T12/10more on Reproduction.

Major questions in developmental biology Single genome Diverse cell types Totipotent zygote Fate refinement Diverse cell fates Cell commitments are largely.
February 06 Developmental biology: imaginal discs 5 wingless hedgehog/engrailed * after several hours of interdependence of wingless and hedgehog: situation.
Chapters #5 and #2. Box 4A wild-type fruit fly antennapedia mutant.
Imaginal discs and what they teach us about morphogens
Day DateReadingTopic T10/15no class – October Vacation Th10/17More plant development T10/22Ch. 8Mechanisms of morphogenesis Th10/24More morphogenesis.
Day DateReadingTopic T 9/2 pp (Ch. 6) C. elegans, model systems, and molecular genetics Watch three Audio/Video handouts: 1A), 1B), and 1C Th9/4Ch.
Day DateReadingTopic T 9/3 pp (Ch. 6) C. elegans, model systems, and molecular genetics Watch three Audio/Video handouts: 1A), 1B), and 1C Th9/5Ch.
Gene Expression and Development II. Final Exam Sunday, May 27, 8:30-11:30 a.m. Here – SMC A110 Please do course evaluations!
Day DateReadingTopic T10/15no class – October Vacation Th10/17More plant development T10/22Ch. 8Mechanisms of morphogenesis Th10/24More morphogenesis T10/29Ch.
M2/25EXAM 1Chapters 1, 3, 4, and pp W2/27Ch. 2More molecular development of Drosophila M3/3CLASS MEETS IN THE LIBRARY, Room 518 of the Glickman.
Development and Genes Part 1. 2 Development is the process of timed genetic controlled changes that occurs in an organism’s life cycle. Mitosis Cell differentiation.
Cellular Mechanisms of Development Chapter 19. Developement Growth (cell division) Differentiation Pattern Formation Morphogenesis.
M2/25EXAM 1Chapters 1, 3, 4, and pp W2/27Ch. 2More molecular development of Drosophila M3/3CLASS MEETS IN THE LIBRARY, Room 518 of the Glickman.
Day DateReadingTopic T 9/3 pp (Ch. 6) C. elegans, model systems, and molecular genetics Watch three Audio/Video handouts: 1A), 1B), and 1C Th9/5Ch.
Chapters #5 and #2. The Hox gene family are examples of homeotic genes. Homeotic genes are genes that when mutant cause a change in the spatial position.
Day DateReadingTopic T10/15no class – October Vacation Th10/17More plant development T10/22Ch. 8Mechanisms of morphogenesis Th10/24More morphogenesis T10/29Ch.
BIO305 Developmental Biology Instructor: Dave Champlin.
Could a nematode give birth to identical twins? No, because the first mitotic division of the zygote is asymmetric.
Biology Developmental Genetics
Genetics of Axis Specification in Drosophila: Dorsal-Ventral Axis Specification Gilbert - Chapter 9.
Day DateReadingTopic T10/15no class – October Vacation Th10/17More plant development T10/22Ch. 8Mechanisms of morphogenesis Th10/24More morphogenesis.
Day DateReadingTopic T 9/2 pp (Ch. 6) C. elegans, model systems, and molecular genetics Watch three Audio/Video handouts: 1A), 1B), and 1C Th9/4Ch.
Drosophila axis detemination; dorsal/ventral polarity How are the embryonic axes set up? How does the embryonic dorsal-ventral axis get translated into.
Animal Development Part 1: Using Drosophila to study pattern formation Petros Ligoxygakis Associate Professor of Genetics.
Day DateReadingTopic T10/15no class – October Vacation Th10/17More plant development T10/22Ch. 8Mechanisms of morphogenesis Th10/24More morphogenesis.
Day DateReadingTopic T 9/2 pp (Ch. 6) C. elegans, model systems, and molecular genetics Watch three Audio/Video handouts: 1A), 1B), and 1C Th9/4Ch.
Your review paper is due at the beginning of class on Tuesday, 11/22
Day Date Reading Topic Th 11/28 no class – Thanksgiving Break
Day Date Reading Topic T 9/3 pp (Ch. 6) C. elegans, model systems, and molecular genetics Watch three Audio/Video.
Day Date Reading Topic T 10/15 no class – October Vacation Th 10/17 More plant development T 10/22 Ch. 8 Mechanisms of morphogenesis Th 10/24 More.
Day Date Reading Topic T 10/15 no class – October Vacation
Drosophila Development: Embryogenesis
Appendage development
Day Date Reading Topic T 10/15 no class – October Vacation
Day Date Reading Topic T 9/3 pp (Ch. 6) C. elegans, model systems, and molecular genetics Watch three Audio/Video.
Gene Regulation During Development
Drosophila Development: Novel Signal Elicits Visceral Response
Genetics of Axis Specification in Drosophila: Anterior-Posterior Axis Determination Gilbert - Chapter 9.
Presentation transcript:

Day DateReadingTopic T10/15no class – October Vacation Th10/17More plant development T10/22Ch. 8Mechanisms of morphogenesis Th10/24More morphogenesis T10/29Ch. 10Cell differentiation Th10/31 Happy Halloween!Stem cells T11/5Ch. 11Organogenesis Th11/7More Organogenesis T11/12 Th11/14Ch. 12Development of the nervous system T11/19EXAM 2Chapters 2, 6, 8, 10 Th11/21Ch. 9 The saga of the germ cell T11/26More on reproductionYour term paper is due at the beginning of class on Tuesday, 11/19 Th11/28no class – Thanksgiving Break Also remember there are two, short writing assignments, each worth 20 points. Pick any topic in developmental biology (except your term paper topic) and learn more about it. Then write a two page paper and include all the sources you used (those can include any sources including web sites, newspapers, TV, etc). These are due anytime.

not in text

Genes to focus on during Drosophila embryogenesis Bicoid Hunchback Even-skipped Engrailed Antennapedia Hedgehog Wingless Gurken Toll Dorsal Decapentaplegic Short gastrulation

2.8 fly A/P axis gene hierarchy

2.37 clones in wing

2.39 Hh/Wg 4 nuclei

2.41 Hh/Wg feedback loop

Box 1E Wnt signal transduction

2.40 Hh signaling pathway

2.8 fly A/P axis gene hierarchy

2.16 oocyte assembly line

2.18 creating posterior follicle cells

From previous edition: Box 2B: Toll/ Dorsal pathway

2.19 Gurken 1

2.20 egg nucleus on motors

*** Gurken signaling turns off pipe expression in “dorsal” follicle cells ***

not in text: Dorsal handout

2.14 Dorsal gradient

2.22 Dorsal gradient

2.23 Dorsal /DPP grad.

2.3 fly cell types

2.7 fly cell types sliced

2.21 D/V slice

Look at the summary paragraphs and associated flow charts throughout Chapter 2: p. 66 Summary: Early Expression of Zygotic Genes

Fig. 2.19