Date of download: 6/28/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Halo Nevus of the Choroid in 150 Patients: The 2010 Henry van Dyke Lecture Arch Ophthalmol. 2010;128(7): doi: /archophthalmol Clinical spectrum of the halo nevus of the choroid. A, Small halo nevus in the macular area with central brown pigment and a surrounding yellow halo. B, Juxtapapillary halo nevus. C, Halo nevus in the temporal macular area with a slightly wider-than-average halo. D, Classic halo nevus of median basal and thickness dimensions. E, Halo nevus with overlying drusen, found in 56.7% of patients. F, Atypical halo nevus with a wider-than-average halo. G, Halo nevus with a slightly internal halo found in 7.3% of patients. H, Reverse halo nevus with a central yellow region and surrounding brown pigmentation. Figure Legend:

Date of download: 6/28/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Halo Nevus of the Choroid in 150 Patients: The 2010 Henry van Dyke Lecture Arch Ophthalmol. 2010;128(7): doi: /archophthalmol Imaging of the halo nevus of the choroid. A and B, Halo nevus with overlying optical coherence tomogram (OCT) demonstrating lack of subretinal fluid or intraretinal edema but with slight opacification in the outer retinal layers. C and D, Halo nevus with overlying OCT showing an intact overlying retina without edema or subretinal fluid. E and F, Halo nevus with a yellow halo showing slight hyperautofluorescence and central pigmented portion and hypoautofluorescence. G, Juxtapapillary halo nevus with a yellow halo showing marked hyperfluorescence on fluorescein angiography and the central pigmented portion showing hypofluorescence. Figure Legend:

Date of download: 6/28/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Halo Nevus of the Choroid in 150 Patients: The 2010 Henry van Dyke Lecture Arch Ophthalmol. 2010;128(7): doi: /archophthalmol Growth of a halo choroidal nevus into melanoma. A, In November 2003, the asymmetric halo nevus and central pigmentation were discovered. B, In December 2004, the nevus had enlarged slightly in basal dimension and thickness, extended under the foveola, and developed overlying subretinal fluid. Note the increase in the central pigmented portion. Treatment was instituted. C, In February 2006, after plaque radiotherapy and thermotherapy, the tumor scar had regressed. Figure Legend: