The FRACTURE Study (Ongoing). Source West SL, Lok CE, Jamal SA. Fracture Risk Assessment in Chronic Kidney Disease, Prospective Testing Under Real World.

Slides:

Advertisements

Similar presentations

Essentials of CKD Comorbidities and outcomes in CKD.

Advertisements

Risk Stratification in Renal Care Mary Jane McKendry Vice President, Operations Fresenius Disease Management Optimal Renal Care.

The Burden of Obesity in North Carolina Obesity-Related Chronic Disease.

The National Kidney Foundations Kidney Early Evaluation Program TM The National Kidney Foundations Kidney Early Evaluation Program TM Essex-Passaic Wellness.

Introduction to Nephrology Sandeep K. Shori, D.O. Dialysis Associates Fort Worth, TX.

The FREEDOM Study (Impact of Short Daily Hemodialysis on Restless Legs Symptoms and Sleep Disturbances) Source Jaber BL, Schiller B, Burkart JM, et al.

CHRONIC KIDNEY DISEASE The Philippine Situation

Lysaght, J Am Soc Nephrol, 2002 Number of patients worldwide treated with chronic dialysis from 1990 to ,000 1,490,000 2,500,000.

Deepa Patel Doctor of Pharmacy Candidate, 2012 Mercer COPHS Presented on July 22, 2011.

The mortality associated with body size and muscle mass, fat mass and abdominal obesity in patients receiving hemodialysis Date: 2012/12/21 實習生：余萍指導老師：蕭佩珍營養師.

Impact of Preoperative Renal Dysfunction in Patients Undergoing Off- pump vs On-pump Coronary Artery Bypass.

Chapter 2: Healthy People A NNUAL D ATA R EPORT V OLUME 2: E ND -S TAGE R ENAL D ISEASE.

Kuala Lumpur, Malaysia, 30 June - 3 July 2013 Abstract: WEABO205. HIV infection was associated with an increased risk of hip fracture,

 Currently 150 Million people worldwide suffering from diabetes and that number may double by the year  The prevalence of type 2 diabetes is dramatically.

* Or unknown (n=8) Inbal Goldshtein 1, Julie Chandler 2, Varda Shalev 1,3, Sofia Ish –Shalom 4, Allison Martin Nguyen 2, Vanessa Rouach 5, Gabriel Chodick.

Reference Cooper BA, and the IDEAL study group. A randomized controlled trial of early versus late initiation of dialysis. N Engl J Med [Accessed.

Dialysis What is it and why do we need it?. What do you already know?

APPENDIX 1. D-1 New cases of diagnosed diabetes D-2.1 All cause mortality* D-2.2 Cardiovascular disease deaths* D-3 Diabetes death rate, multiple cause.

Chapter 3: Morbidity & Mortality 2014 ANNUAL DATA REPORT VOLUME 1: CHRONIC KIDNEY DISEASE.

Hemoglobin A 1c in Hemodialysis Patients Source: Ix JH. Hemoglobin A1c in hemodialysis patients: Should one size fit all? Clin J Am Soc Nephrol. 2010;5:1539–1541.

RENAL DISEASE IN DIABETES

EPIDEMIOLOGY Epidemiology of chronic kidney injury, including prevalence and prognosis in various community groups. Screening of populations for kidney.

6 / 5 / RENAL DISEASE OUTCOMES IN HYPERTENSIVE PATIENTS STRATIFIED INTO 3 GROUPS BY BASELINE GLOMERULAR FILTRATION RATE (GFR) ALLHAT.

PREDICTING AKI IS MORE CHALLENGING AS AGE PROGRESSES Sandra Kane-Gill, PharmD, MSc Associate Professor, School of Pharmacy.

‘STROKE’ February 2011 Dr Amer Jafar ABHB/Gwent. Decreased Kidney Function  Chronic kidney disease is an important risk factor for development and progression.

CHRONIC KIDNEY DISEASE National Healthcare Quality and Disparities Report Chartbook on Effective Treatment.

Mrs. Watcharasa Pitug ID The Association between Waist Circumference and Renal Insufficiency among Hypertensive Patients 20/10/58 1.

Healthy People 2010 Focus Area 4

2015 ANNUAL DATA REPORT V OLUME 2: E ND -S TAGE R ENAL D ISEASE Chapter 2: Healthy People 2020.

Federal Register, May 4, New ICD-9-CM codes for CKD, showing revisions Revise585Chronic renal failure Chronic kidney disease (CKD) AddUse additional.

Preoperative Hemoglobin A1c and the Occurrence of Atrial Fibrillation Following On-pump Coronary Artery Bypass surgery in Type-2 Diabetic Patients Akbar.

Location and Types of Falls Among Older Adults. Location of Falls among Older Adults 1,2 1 among those with known location 2 Source: Ohio Hospital Association.

Chronic Kidney Disease (CKD) Healthy Kansans 2010.

1 Antonio Bellasi, MD Medical manager Genzyme, Italy Chronic Kidney Disease-Mineral Bone Disorders (CKD-MBD)

Falls and Fall Prevention. Prevalence of Falls in Older Adults  33% of older adults fall each year  Falls are the leading cause of fatal and nonfatal.

High Coronary Calcification Scores Predict Mortality in Pre-Dialysis CKD Patients Reference: Haas MH. The risk of death in patients with a high coronary.

The DVD Trial. Source Reinecke H, Fobker M, Wellmann J, et al. A randomized controlled trial comparing hydration therapy to additional hemodialysis or.

Date of download: 6/2/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Similar Outcomes With Hemodialysis and Peritoneal.

The RAVE Study Renal Athersosclerotic Revascularization Evaluation Reference Tobe SW, Atri M, Perkins N, et al. Renal Athersosclerotic revascularization.

Chronic Haemodialysis therapy in octogenarians with ESRF: demographics and outcomes from a single centre in England Dr Punit Yadav Dr Jyoti Baharani.

Acute Renal Failure in HIV- Infected Individuals Greatly Increases Risk for In-Hospital Mortality Slideset on: Wyatt CM, Arons RR, Klotman PE, Klotman.

INTRODUCTION South Africa has the highest reported incidence of tuberculosis (TB) globally at 860 cases per per year, and the third highest absolute.

HIV-associated CKD (HIV-CKD) Studies from Africa have shown a variable prevalence of renal disease in HIV, ranging from 6% to 45% : (6% in SA, 38% in.

The SYMPHONY Trial Reference Reddan DN, et al. Renal function, concomitant medication use and outcomes following acute coronary syndromes. Nephrol Dial.

The CHART-2 Study (The Chronic Heart Failure Analysis and Registry in the Tohoku District 2) Source Shiba N, Nochioka K, Miura M, et al. Trend of westernization.

Is it possible to predict New Onset Diabetes After Transplantation (NODAT) in renal recipients using epidemiological data alone? Background NODAT is an.

The FRET Study Source: Inoue T, Ikeda H, Nakamura T, et al. Potential benefit of statin therapy for dyslipidemia with chronic kidney disease: Fluvastatin.

Anemia in CKD The TREAT Trial Reference Pfeiffer MA. A trial of Darbepoetin alpha in type II diabetes and chronic kidney disease. N Engl J Med. 2009;361:2019–2032.

Introduction Data Statistical Methods Table 1: Prevalence of Prior Hip Fracture and Incidence of New Hip Fractures and Fractures of Any Type.

Preemptive Kidney Transplant (PKT) – the Optimal Therapy in ESRD Reference: Connie L. Davis. Preemptive transplantation and the transplant first initiative.

Acute Renal Failure in Aneurysmal Subarachnoid Hemorrhage: Nationwide Analysis of Hospitalizations in the United States Kavelin Rumalla 1, Adithi Y. Reddy.

The FAVORIT Study (Folic Acid for Vascular Outcome Reduction in Transplantation) Source Bostom AG, Carpenter MA, Kusek JW, et al. Homocysteine-lowering.

Statins The AURORA Trial Reference Fellstrom BC. Rosuvastatin and cardiovascular events in patients undergoing hemodialysis. N Engl J Med. 2009;360. A.

Renal Replacement Therapy for Prevention of Contrast- induced Acute Kidney Injury: A Meta-analysis of Randomized Controlled Trials Source Song K, Jiang.

The presence of cardiovascular disease is an important predictor of mortality in patients with end-stage renal disease, as it accounts for almost 50 percent.

－ Higher SBP visit-to-visit variability (SBV) has been associated

The LIVES Sub-analysis

A.M. Thompson, T.G. Pickering Kidney International

Golden Rules to Keep Kidneys Healthy

Section 3: CKD, CVD and mortality

The ECHO Observational Study

The IDEAL Study Reference

Figure 4 Interplay between acute kidney injury (AKI),

Diagnosing Vertebral Fractures

Volume 83, Issue 3, Pages (March 2013)

Figure 1 The burden of chronic kidney disease (CKD)

Figure 2 The continuum of acute kidney injury (AKI),

A Six-hour Hemodialysis Without a Significant Increase in Dialysis Dose, as Judged by Kt/V, Can Reduce the Dosage of Erythropoietin Department of Kidney.

Targeting Immunity in End-Stage Renal Disease

Fistula and Survival Outcomes after Fistula Creation among Predialysis Chronic Kidney Disease Stage 5 Patients Miyamoto et al. Am J Nephrol 2017;45:

Presentation transcript:

The FRACTURE Study (Ongoing)

Source West SL, Lok CE, Jamal SA. Fracture Risk Assessment in Chronic Kidney Disease, Prospective Testing Under Real World Environments (FRACTURE): a prospective study. BMC Nephrol. 2010;11:17.

Background Chronic kidney disease (CKD) is associated with an increased risk of fracture with nearly half of the patients having history of fracture at the time of initiation of dialysis. In a study, it was observed that the incidence of hip fractures in a hemodialysis population was 17.4 times greater and occurred at a younger age compared to the general population. Despite the excess fracture risk, and the associated increases in morbidity and mortality, little is known about the factors that are associated with an increase in fracture risk.

Aim To identify prognostic factors for bone loss and fractures in patients with stages 3–5 CKD.

Methods

Conclusion This study has been designed to expand the current knowledge of prognostic factors for fracture in end-stage renal disease to the CKD stage 3–5 population. It would also address some of the existing knowledge gaps in the identification, diagnosis, and interpretation of bone disease and fracture risk in CKD. This study aims to identify risk factors for fracture in early-stage CKD thereby helping in reducing the burden of disease due to fractures among this patient population.