EBM process – 4 steps Question? Search for information Critical review Application ······················································································

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Presentation transcript:

EBM process – 4 steps Question? Search for information Critical review Application ······················································································

The main step Search for information 1. Search wide (high sensitivity) 2. Limit irrelevant hits (high specificity) 3. Use a good hit to find other relevant articles ······················································································

Choose the right database Search for information in this order: 1. The Cochrane Library 2. Mega-search engine (SUMSearch) 3. Other secondary databases (BestBets) 4. Clinical guidelines (Clinical Evidence) 5. …first now MEDLINE (PubMed) ······················································································

Some addresses ······················································································

Evaluation of scientific quality Why?- Purpose In what way?- Design How good?- Quality How large?- Effect size How accurate?- Reliability So what?- Relevance/Importance ······················································································

The level of evidence LevelMeaning Background AGood Meta-analysis, syst. reviews. large RCT BModerate Small RCT, cohort-, case- control- and cross sectional studies CLow Case reports, expert opinion DNone No studies available ······················································································