Screening for CAD Nuclear Medicine prospective S.R.Zakavi,MD,IBNM Nuclear Medicine Research Center Mashhad University of Medical Sciences

Screening for CAD Detection of Coronary artery disease in : Symptomatic Asymptomatic

Detection of ischemia with MPI Who?

Zakavi,MD.

Detection of chronic CAD with MPI ( Class I in symptomatic patients / intermediate risk ) Stress imaging should be used. Very sensitive and specific method. Routinely used as a gate keeper for angiography. Disease severity and prognosis are also evaluated. Zakavi,MD.

AUC 2009 Zakavi,MD.

Screening for CAD in Asymptomatic patients

In Diabetics Increasing prevalence of DM specially in developing world CAD is the most common cause of death in type 2 DM patients. Multivariate analysis has shown that MPI abnormalities, retinopathy and duration of diabetes are independent predictors of cardiac events. Circulation 2002,

In asymptomatic diabetics CAD is frequently asymptomatic in diabetic patients. DIAD study : 2.9% cardiac event during follow up. Our study: 3.2% cardiac events. J Nucl Cardiol 2009:

AUC Asymptomatic patients J. Am. Coll. Cardiol. 2009;

AUC Asymptomatic patients

Rapid technology progress With each new technological advance comes pressure for immediate implementation and dissemination, often before evidence of efficacy has been published. Circulation, 27 Sep,2011