Four Levels of Protein Structure

Slides:

Advertisements

Similar presentations

Proteins Review. Learning outcomes (e) Describe the structure of an amino acid and the formation and breakage of a peptide bond. (f) Explain the meaning.

Advertisements

Organic Nutrients: The Building Blocks of Life 1. Carbohydrates 2.Lipids 3.Proteins 4.Nucleic Acids.

Proteins & Nucleic Acids Images taken without permission from

Biology 107 Macromolecules II September 9, Macromolecules II Student Objectives:As a result of this lecture and the assigned reading, you should.

Polypeptides – a quick review A protein is a polymer consisting of several amino acids (a polypeptide) Each protein has a unique 3-D shape or Conformation.

Biology 107 Macromolecules II September 8, 2003.

1. Primary Structure: Polypeptide chain Polypeptide chain Amino acid monomers Peptide linkages Figure 3.6 The Four Levels of Protein Structure.

Proteins Structures Primary Structure.

Amino acid side chains stabilise the enzyme shape.

Daily Starter  Explain how a peptide bond is formed. (What is the reaction called and how does it happen?)

Homework for next week Green q 1,2,3 p29 Do evaluation points from Biuret Practical Revise test on all work next week Bring evidence you have revised please.

Biomolecules: Nucleic Acids and Proteins

Proteins and DNA Chapter 3.

Building Complex Molecules That Comprise Living Things

Diverse Macromolecules. V. proteins are macromolecules that are polymers formed from amino acids monomers A. proteins have great structural diversity.

Review of Biological Chemistry. Biologically Important Elements.

Objectives E – Recall the different structures of proteins and the test for proteins. C – Describe how a peptide bond is formed. Describe the different.

Macromolecules Building Complex Molecules That Comprise Living Things.

Macromolecules Building Complex Molecules That Comprise Living Things.

Proteins!. Proteins Proteins account for more than 50% of the dry mass of most cells Monomer: amino acids 20 amino acids used in cells Central carbon.

Proteins & DNA. Amino Acids: the building blocks of Proteins.

Proteins. Slide 2 of 19 Proteins  Polymers composed of amino acids  Protein = Polypeptide (polymer)  Monomer = Amino acids  Peptide bonds  Amino.

Biological Molecules. Life is carbon-based chemistry Hydrolysis and Synthesis of Biological Molecules Carbohydrates Lipids Proteins Nucleic Acids.

Proteins Pgs Pgs Allosteric Enzymes  Allosteric enzymes have 2 sites. Active site of the enzyme Additional site where another substance.

Building Complex Molecules That Comprise Living Things

Carbon Compounds Chapter 2 Section 3 Part 2. Objectives  Describe the unique qualities of carbon  Describe the structures and functions of each of the.

BIOLOGICALLY IMPORTANT MACROMOLECULES PROTEINS. A very diverse group of macromolecules characterized by their functions: - Catalysts - Structural Support.

The Structure of Proteins. Functions of Proteins Fibrous proteins – structural, e.g. collagen. Globular proteins – metabolic functions, e.g. haemoglobin.

Amino Acids & Proteins The Molecules in Cells Ch 3.

Protein Structure and Enzyme Function

Macromolecules Building Complex Molecules That Comprise Living Things.

Protein- Secondary, Tertiary, and Quaternary Structure.

1 Proteins Proteins are polymers made of monomers called amino acids All proteins are made of 20 different amino acids linked in different orders Proteins.

Protein Structure  The structure of proteins can be described at 4 levels – primary, secondary, tertiary and quaternary.  Primary structure  The sequence.

Proteins pp Proteins Proteins are used for: Amino acids.

Proteins. Functions of Proteins Some Functions of Proteins Type of proteinExampleFunction Enzymes amylasePromotes the break down of starch to the simple.

Levels of Protein Structure. Why is the structure of proteins (and the other organic nutrients) important to learn?

Functions Enzymes – organic catalysts Structural – skin, hair, muscle Antibodies Hormones.

Proteins Proteins are the building materials for the body.

6.9 Attractive Forces in Compounds

PROTEINS and ENZYMES!.

Chapter 6: Proteins and Amino Acids

Chapter 6: Proteins and Amino Acids

Amino Acids and Proteins

Good Morning! No bell ringer this morning.

Proteins Made of amino acids in a specific sequence attached by peptide bonds. Consist primarily of carbon, hydrogen, oxygen, and nitrogen, but may include.

Primary, secondary, tertiary and quaternary structures.

Macromolecules: Proteins

Building Complex Molecules That Comprise Living Things

PROTEINS and ENZYMES!.

Diverse Macromolecules

Study Question: What are enzymes?

Protein Structure Chapter 14.

Tertiary and Quaternary Protein Structure

Proteins C, H, N, O, S 50% of the Dry Weight of Living Organisms

PROTEINS, The Stuff of Life.

Daily Science In forming a protein, why is it important that every amino acid has the same structure of a carboxyl group on one side and amino group on.

Nucleic Acids Structure Cellular Function.

Bell ringer - Phospholipids

Four Levels of Protein Structure

2.4 - Proteins.

Presentation transcript:

Four Levels of Protein Structure

Four Levels of Protein Structure Primary Structure: Linear Sequence of Amino Acids Each amino acid has central carbon liked to ---hydrogen (H) ---amino group (NH2) ---acid group (COOH) ---unique group (R) O H H2N C C R OH

The carboxyl group of one amino acid is linked to the amino group of the next amino acid.

Four Levels of Protein Structure Primary Structure: Amino Acids are linked with a covalent bond called a peptide bond. O H H H O H2N C C N C C OH R1 R2

Four Levels of Protein Structure Secondary Structure: Folded structure due to hydrogen bonds between the amino and acid groups of amino acids N C N C H H O O or O H O H C N C N

Four Levels of Protein Structure Tertiary Structure: Three dimensional folded structure due to attractions and repulsions between R groups All but peptide bonds are involved in tertiary structure.

Four Levels of Protein Structure Quaternary structure: Association of two or more protein chains eg. Hemoglobin is composed of 4 protein chains 2 are called alpha hemoglobin 2 are called beta hemoglobin

Applying Your Knowledge Primary Secondary Tertiary Quaternary Which structure results exclusively from hydrogen bonding? Which structure involves an association of two or more protein chains? Which structure describes the linear sequence of amino acids? Which structure depends upon interactions between the R groups of the amino acids?