Multiscale Thermofluid Engineering Laboratory 1 Oxygen Transport in Blood Flows Past Staggered Fiber Arrays: A Computational Fluid Dynamics Study of an.

Slides:

Advertisements

Similar presentations

A mathematical model of steady-state cavitation in Diesel injectors S. Martynov, D. Mason, M. Heikal, S. Sazhin Internal Engine Combustion Group School.

Advertisements

Turbulent flow over groups of urban-like obstacles

O 2 AND Athletic Performance. ALVEOLI IN THE LUNG Alveoli are the places where gas exchange occurs in the lung. Why is surface area an important consideration.

Usefulness of velocity profiles based on 3D cine PC MR used as boundary conditions for computational fluid dynamics of an intracranial aneurysm : investigation.

Hongjie Zhang Purge gas flow impact on tritium permeation Integrated simulation on tritium permeation in the solid breeder unit FNST, August 18-20, 2009.

Design and Optimization of Molten Carbonate Fuel Cell Cathodes Bala S. Haran, Nalini Subramanian, Anand Durairajan, Hector Colonmer, Prabhu Ganesan, Ralph.

Example: Electrokinetic valve

Direct Forcing Immersed Boundary (DFIB) Method for Mixed Heat Transfer

Ta-Te Lin, Yi-Chung Chang

Gaseous And Particulate Dispersion In Street Canyons

An Analysis of Hiemenz Flow E. Kaufman and E. Gutierrez-Miravete Department of Engineering and Science Rensselaer at Hartford.

Transport phenomena in chemical processes part III Michał Araszkiewicz PhD.

Experimental and Numerical Study of the Effect of Geometric Parameters on Liquid Single-Phase Pressure Drop in Micro- Scale Pin-Fin Arrays Valerie Pezzullo,

MECH 221 FLUID MECHANICS (Fall 06/07) Chapter 9: FLOWS IN PIPE

University of South Carolina FCR Laboratory Dept. of Chemical Engineering By W. K. Lee, S. Shimpalee, J. Glandt and J. W. Van Zee Fuel Cell Research Laboratory.

CE 1501 CE 150 Fluid Mechanics G.A. Kallio Dept. of Mechanical Engineering, Mechatronic Engineering & Manufacturing Technology California State University,

California State University, Chico

DETAILED TURBULENCE CALCULATIONS FOR OPEN CHANNEL FLOW

Instability of electro-osmotic channel flow with streamwise conductivity gradients Brian Storey Jose Santos Franklin W. Olin College of Engineering Needham.

Flow and Thermal Considerations

Convection Prepared by: Nimesh Gajjar. CONVECTIVE HEAT TRANSFER Convection heat transfer involves fluid motion heat conduction The fluid motion enhances.

Chilton and Colburn J-factor analogy

Enhanced Heat Exchange Using Microchannel Array Architectures School of Chemical, Biological, and Environmental Engineering Ted Carter and Paula Pérez.

法洛氏四重症術後之肺動脈流場型態分析 Analysis of flow patterns in pulmonary artery after repair of Tetralogy of Fallot Hung-Lin Wang June 14, 2006.

© 2011 Autodesk Freely licensed for use by educational institutions. Reuse and changes require a note indicating that content has been modified from the.

Artificial lung Done by : Eng.Samar.T.Alqattan

Respiratory Dynamics 7.3. Red Blood Cells Also called erythrocytes The primary function is to transport oxygen from the lungs to the tissues and remove.

Nathaniel D. Barnett 1 and E. Gutierrez-Miravete 2 1 General Dynamics-Electric Boat 2 Rensselaer-Hartford COMSOL-09.

Mass Transfer Coefficient

Laboratoire Environnement, Géomécanique & Ouvrages Comparison of Theory and Experiment for Solute Transport in Bimodal Heterogeneous Porous Medium Fabrice.

Transport of deuterium - tritium neutrals in ITER divertor M. Z. Tokar and V.Kotov Plasma and neutral gas in ITER divertor will be mixed of deuterium and.

MODELLING OF MULTIPHASE FLOWS OVER SURFACE WITH PENETRABLE ROUGH RELIEF Yevgeniy A. Shkvar National Aviation University, Kyiv, Ukraine

Convective Heat Transfer in Porous Media filled with Compressible Fluid subjected to Magnetic Field Watit Pakdee* and Bawonsak Yuwaganit Center R & D on.

A RANS Based Prediction Method of Ship Roll Damping Moment Kumar Bappaditya Salui Supervisors of study: Professor Dracos Vassalos and Dr. Vladimir Shigunov.

Physical Fluid Dynamics by D. J. Tritton What is Fluid Dynamics? Fluid dynamics is the study of the aforementioned phenomenon. The purpose.

INTRODUCTION Many heat and mass transfer processes in column apparatuses may be described by the convection – diffusion equation with a volume reaction.

Compressor Cascade Pressure Rise Prediction

Analogies among Mass, Heat, and Momentum Transfer

Convection in Flat Plate Boundary Layers P M V Subbarao Associate Professor Mechanical Engineering Department IIT Delhi A Universal Similarity Law ……

Lecture #6 Ehsan Roohi Sharif University of Technology Aerospace Engineering Department 1.

Compressible Frictional Flow Past Wings P M V Subbarao Professor Mechanical Engineering Department I I T Delhi A Small and Significant Region of Curse.

이 동 현 상 (Transport phenomena) 2009 년 숭실대학교 환경화학공학과.

Fluid Mechanics SEMESTER II, 2010/2011

Laminar Flow Convective Heat Transfer

Fluid Mechanics Credit Hours 4(3+1)

FLUID MECHANICS AND MACHINERY Department of Mechanical Engineering Department.

MULTI-COMPONENT FUEL VAPORIZATION IN A SIMULATED AIRCRAFT FUEL TANK C. E. Polymeropoulos Department of Mechanical and Aerospace Engineering, Rutgers University.

1. Integral vs Differential Approach

Thermo-aero Dynamic Analysis of Wind Turbines P M V Subbarao Professor Mechanical Engineering Department Development of Characteristic Design Variables.

Arjun Bahl, Cameron Hinkel, and Ben Jiang – Group 28 Mentor: David Hoganson, MD.

Heat Transfer Su Yongkang School of Mechanical Engineering # 1 HEAT TRANSFER CHAPTER 6 Introduction to convection.

Heat Transfer Su Yongkang School of Mechanical Engineering # 1 HEAT TRANSFER CHAPTER 7 External flow.

Artificial Lung Medical device to take over or supplement the respiratory function of the lungs. Used in cardiopulmonary bypass for open-heart surgery.

Heat Transfer in a Packed Bed Reactor with Downflow of Air and Water

Hamdache Abderrazaq 1*, Belkacem Mohamed 1, Hannoun Nourredine 2

Date of download: 10/10/2017 Copyright © ASME. All rights reserved.

Chap.6 Fuel Cell modeling

Prepared BY: Helwan University Faculty Of Engineering

11th International Conference on Mechanical Engineering (ICME2015)

Design of Passive (Adiabatic) Control Volumes

The Human Body Chemical Plant reactions membrane separations

Numerical Modeling of Dynamics and Adhesion of Leukocytes

Space Distribution of Spray Injected Fluid

Lattice Boltzmann Simulation of Water Transport in Gas Diffusion Layers of PEMFCs with Different Inlet Conditions Seung Hun Lee1, Jin Hyun Nam2,*, Hyung.

FLUID MECHANICS REVIEW

Diffusion Across Channels and Along Pores

Fluid Mechanics Lectures 2nd year/2nd semister/ /Al-Mustansiriyah unv

Extracorporeal life support during pregnancy

Convective Heat Transfer

Presentation transcript:

Multiscale Thermofluid Engineering Laboratory 1 Oxygen Transport in Blood Flows Past Staggered Fiber Arrays: A Computational Fluid Dynamics Study of an Oxygenator in Artificial Lung Yu-Chen Hsu & Kuang C. Lin Department of Mechanical and Electromechanical Engineering, National Sun Yat-Sen University, Kaohsiung, Taiwan

Multiscale Thermofluid Engineering Laboratory 2 Kaohsiung National Sun Yat-Sen University

Multiscale Thermofluid Engineering Laboratory 3 PROCESS DESCRIPTION PRESENT

Multiscale Thermofluid Engineering Laboratory 4 PROCESS DESCRIPTION BACKGROUND COMPUTER MODEL GOVERNING EQUATIONS ANALYSIS and CONCLUSIONS

Multiscale Thermofluid Engineering Laboratory 5 B BACKGROUND

Multiscale Thermofluid Engineering Laboratory 6 BACKGROUND Simple description Extracorporeal Membrane Oxygenation

Multiscale Thermofluid Engineering Laboratory 7 BACKGROUND H1N1 virus 1.Acute Lung Injury (ALI) 2.Acute Respiratory Distress Syndrome (ARDS) Cardiopulmonary diagram

Multiscale Thermofluid Engineering Laboratory 8 M. Ertan Taskin et al “Micro-scale modeling of flow and oxygen transfer in hollow-fiber membrane bundle” Journal of Membrane Science (2010) BACKGROUND Reference

Multiscale Thermofluid Engineering Laboratory 9 Fig. Comparison of the mini-oxygenator model predicted and benchmark device measured SO2 and m˙ O2 profiles along the fiber region. BACKGROUND Reference Consideration of pulsating flow (mimicking heart pumping) in this benchmark device.

Multiscale Thermofluid Engineering Laboratory 10 C COMPUTER MODEL

Multiscale Thermofluid Engineering Laboratory 11 COMPUTER MODEL Outlet – pressure outlet Wall – stationary and no slip wall Fig. Schematic of the computational domain

Multiscale Thermofluid Engineering Laboratory 12 Inlet Boundary Conditions COMPUTER MODEL

Multiscale Thermofluid Engineering Laboratory 13 Inlet Boundary Conditions COMPUTER MODEL ECMO Reynolds numberWomersley parameters Amplitude of blood flow

Multiscale Thermofluid Engineering Laboratory 14 COMPUTER MODEL

Multiscale Thermofluid Engineering Laboratory 15 Fiber Region COMPUTER MODEL 83 Fibers Fig. zoom-in view of the fiber bundle

Multiscale Thermofluid Engineering Laboratory 16 G GOVERNING EQUATIONS

Multiscale Thermofluid Engineering Laboratory 17 GOVERNING EQUATIONS Continuity equation Momentum equation Convection-diffusion equation

Multiscale Thermofluid Engineering Laboratory 18 Non-Newtonian-Power-Law model Non-Newtonian fluid (shear-thickening) Newtonian fluid Non-Newtonian fluid (shear-thinning) N.S.K. Chaitanya et al International Journal of Heat and Mass Transfer (2012) GOVERNING EQUATIONS

Multiscale Thermofluid Engineering Laboratory 19 Diffusion coefficient The oxygen binding capacity per volume of blood in STP assumption (0.167 ml Hb/ml) GOVERNING EQUATIONS

Multiscale Thermofluid Engineering Laboratory 20 A ANALYSIS

Multiscale Thermofluid Engineering Laboratory 21 Relative deviation (RD) ANALYSIS Parameters

Multiscale Thermofluid Engineering Laboratory 22 ANALYSIS Position L = 0 L = 1

Multiscale Thermofluid Engineering Laboratory 23 ANALYSIS M. Ertan Taskin et al Journal of Membrane Science (2010)

Multiscale Thermofluid Engineering Laboratory 24 ANALYSIS M. Ertan Taskin et al Journal of Membrane Science (2010)

Multiscale Thermofluid Engineering Laboratory 25 ANALYSIS Position 26D Location of where PO2 is analyzed

Multiscale Thermofluid Engineering Laboratory 26 ANALYSIS M. Ertan Taskin et al Journal of Membrane Science (2010) overpredict

Multiscale Thermofluid Engineering Laboratory 27 C CONCLUSIONS

Multiscale Thermofluid Engineering Laboratory 28 CONCLUSIONS STEADY vs UNSTEADY First R elative deviation around 0% - 13%. The maximum of r elative deviation is located at fist layer of fibers.

Multiscale Thermofluid Engineering Laboratory 29 CONCLUSIONS Amplitude Influence Second As the Reynolds number increases, the influence of the flow amplitude on oxygen transport is pronounced. This phenomenon explains why a heart beats vigorously when human body is in a deoxygenated situation. The effect of Reynolds number is minor whereas the amplitude effect on oxygen transport is the significant.

Multiscale Thermofluid Engineering Laboratory Consideration of pulsating blood flows in oxygen transport of artificial lung is necessary especially in greater Reynolds number. 30 CONCLUSIONS Take-home message

Multiscale Thermofluid Engineering Laboratory 31 CONCLUSIONS Take-home message Although oxygen transport in blood flows is mitigated at high heart beating rates, an increase of flow amplitude is able to compensate insufficient oxygen concentrations in blood flows.

Multiscale Thermofluid Engineering Laboratory 32