Date of download: 7/5/2016 Copyright © ASME. All rights reserved. From: Validation of Cardiac Output as Reported by a Permanently Implanted Wireless Sensor J. Med. Devices. 2015;10(1): doi: / CardioMEMS HF system with wireless PA pressure sensor implant (left) and patient home electronics unit (right) Figure Legend:

Date of download: 7/5/2016 Copyright © ASME. All rights reserved. From: Validation of Cardiac Output as Reported by a Permanently Implanted Wireless Sensor J. Med. Devices. 2015;10(1): doi: / In Vitro mock circulation used to validate the CardioMEMS HF system CO measurement Figure Legend:

Date of download: 7/5/2016 Copyright © ASME. All rights reserved. From: Validation of Cardiac Output as Reported by a Permanently Implanted Wireless Sensor J. Med. Devices. 2015;10(1): doi: / o Patient-specific pulmonary artery anatomy acquired from CT angiogram. The CardioMEMS pressure sensor location is highlighted by the circle. Figure Legend:

Date of download: 7/5/2016 Copyright © ASME. All rights reserved. From: Validation of Cardiac Output as Reported by a Permanently Implanted Wireless Sensor J. Med. Devices. 2015;10(1): doi: / An example of pulmonary artery pressure waveform from an implanted CardioMEMS sensor with relevant parameters. Pd, diastolic pressure; mSPAP, mean systolic pulmonary artery pressure; Pi, pressure at RV incident; and Ps, pressure at peak systole. Figure Legend:

Date of download: 7/5/2016 Copyright © ASME. All rights reserved. From: Validation of Cardiac Output as Reported by a Permanently Implanted Wireless Sensor J. Med. Devices. 2015;10(1): doi: / Pressure waveforms from each of the modeled physiological conditions as recorded by the CardioMEMS HF system. DLHF, decompensated left heart failure and PH, pulmonary hypertension. Figure Legend:

Date of download: 7/5/2016 Copyright © ASME. All rights reserved. From: Validation of Cardiac Output as Reported by a Permanently Implanted Wireless Sensor J. Med. Devices. 2015;10(1): doi: / Bland–Altman plot indicating the fixed and proportional bias between the reference CO measurement and the CO estimated by the CardioMEMS system, over the presented range of simulated benchtop hemodynamic conditions, with three repetitions. The dashed lines indicate the 95% limits of agreement. Figure Legend:

Date of download: 7/5/2016 Copyright © ASME. All rights reserved. From: Validation of Cardiac Output as Reported by a Permanently Implanted Wireless Sensor J. Med. Devices. 2015;10(1): doi: / Bland–Altman analyses of CardioMEMS HF system CO measurement per simulated physiological condition. PH, pulmonary hypertension; DLHF, decompensated left heart failure; and CMHFS, CardioMEMS heart failure system. Figure Legend:

Date of download: 7/5/2016 Copyright © ASME. All rights reserved. From: Validation of Cardiac Output as Reported by a Permanently Implanted Wireless Sensor J. Med. Devices. 2015;10(1): doi: / CO change analysis. The baseline calibration set point (CO = 4.9 l/min) is used as the origin. Figure Legend: