VCDE WS in EY2 Where we are, where we’re going ICR WS Teleconference Brian Davis – VCDE WS Lead March 26, 2008

Where we are: Projects involving VCDE WS Participants Mentoring Silver Level Compatibility Reviews CDE Standard Reviews Vocabulary Standard Reviews Ad Hoc Working Groups Development Projects LexBIG Compatibility Review Software (CRS) System

Mentoring PROJECTMentor caTissue SuiteBaris XIPBob AIMBaris PROJECTMentor Middleware (2)Sal TrWorkbenchBaris New GenepatternQuan caMOD(2)Quan +40 more

Silver Compatibility review PROJECTLead reviewerTeam geWorkbenchQuanMukesh, Sal BioconductorSalQuan, Mukesh MiddlewareSalKristel, Mike R, Grace, Sri, Janice ChembankGraceLinda, Sal, Baris caARRAYSalSri, Mukesh, Kristel, Grace, Xin, Quan, Baris C3PRXinSri, Sal CCTSiLewisLynne, Xin, Kristel caXchangeLynneQuan, Linda, Sal, Sri caAERSLynneSri, Kristel, Stuart, Lewis Patient StudyKristelQuan, Sri caIntegrator (#2)BobQuan, Sal, Sri, Baris XIPBobnone as yet AIMBarisBob, Sal

CDE Standard and Vocab reviews CDE PROJECTLeadsTeam CDE Modification ReviewLynneRakesh, Mary, Janice, Kristel, Dianne, Linda, Baris, Mukesh UCUMLynneRakesh, Kristel, Mary AJCC StagingMukeshLynne, Linda, Mary LOINCRakeshLynne, Kristel, Mary Vocabulary ProjectLeadsTeam SNOMEDStuartSal, Mike R, Hua, Mayo, Gulfstream, John Kilbourne, Persistent RxNormGraceGulfstream, Persistent, others

Ad Hoc Working Groups PROJECTLeadTeam (VCDE) Analytical Services Best PracticesTedBaris CDE Standards Submission Pkg.LynneSal, Kristel, Grace, Mary Terminology MetadataTomSal, Hua, Frank, Denise, Mike R WorkflowKiranBaris Binary DataScottJoyti Ontology-Based Query on caGridHaroldJoyti, Rakesh, Denise, Frank, Hua, Janice UML Gold CriteriaBobLewis, Rakesh, Claire Vocab Gold CriteriaSalLarry, Craig S, Stuart CDE Gold CriteriaLynneBaris, Dianne Dynamic ExtensionsBrianBaris, Linda, Kristel

Developer Projects PROJECTDevelopers/Adopters LexBIGTom et al/Frank et al (Mayo/EVS) CRSRakesh et al/Bob et al (Wash U/Mayo)

Where we are going: Vision (Web Site) The Vocabularies and Common Data Elements (VCDE) Workspace will be responsible for evaluating and integrating systems for vocabulary, common data elements (CDE) and ontology content development, as well as software systems for content delivery. They will also be responsible for developing standards for the representation of ontologies and vocabularies, as well as for assessments of existing systems proposed for use within the caBIG. In addition, this workspace will have responsibility for vocabulary, CDE and ontology content development, when specific and required content does not exist in a form usable by caBIG.

From Jan 2008 F2F The VCDE Workspace is charged with ensuring semantic compatibility interoperability Develop caBIG™ compatibility guidelines in the areas of information modeling, metadata and vocabularies Provide mentors to caBIG™ funded development projects in the area of information modeling, metadata and vocabularies Facilitate development of caBIG™ data standards, both vocabularies and CDEs Perform compatibility reviews of caBIG™ funded development projects to ensure compliance with compatibility guidelines for semantics

From Jan 2008 F2F Development of Federated Vocabulary Environment using caGrid Implementation of Concept ID on caGrid Convergence of LexBIG, caCORE, EVS and NCBO Browser “Industrialize” vocabulary standard review and approval Continued identification of “high impact” data standards Increased Data standard submissions from Domain Workspaces for review and approval (i.e. BRIDG) Bridging Gap between UML model and CRF standards Integration with other Biomedical Research Grids/Organizations Interoperability with NCRI/ONIX Federal Health Architecture/National Health Information Network

Compatibility -> Interoperability Interoperability Strategies Goal Tactics Projects Gold Compatibility Vocab Standards Service Providers Standards LexBIG Increased Standards Bodies Activities Closer relation with Domain WS Projects Backbone Model Knowledge Centers (KC) caDSR CRS SIW Gold Criteria Silver and Gold Reviews CDE Standards Ontology- Query Mentor Domain WS Increased Standards Bodies Activities Interaction with KC and Ser.Pro. Closer relation with Domain WS Projects Increased Standards Bodies Activities Interaction with KC and Ser.Pro. Ad Hoc Groups

GOALS March 2008 to March 2009 INTEROPERABILTY Mentoring all caBIG-funded and NCICB projects (40+) All others to be done by Compatibility KC Limited number of Compatibility reviews (10+) Gold, “Bundles” All others done by Service Providers Vocabulary Reviews (5-7) CDE Reviews (20 “Sets”) Gold Level Compatibility Guidelines, conformance, reviews Harmonization of Models across caBIG Outward facing activities Domain WS, Standards Bodies, Grids, Software that affects Interoperability

Structure of VCDE WS How do we accomplish all these: VCDE WS Participants!!! TECHNICAL interaction with “Permanent Group Leadership”: “Guides to Mentors” plus “Liaison” Activites  “Guides (SuperMentors)” Guide for each Domain WS Mentors to each project interact with “Guide” Oversight of Mentors and Compatibility Review (40 + projects) CDE Leadership List of CDEs for standards CDE Standards from Backbone model, from Domain WS, From Content Admins, and “other” Oversight of CDE Review Vocabulary Leadership List of Vocabs to review Oversight of Vocab review Backbone Model Oversight group Backbone Modelers Oversight of Backbone model (with Domain Workspaces)

Technical Interactions among VCDE WS Participants George DanielaBrianMike FrankDianeDeniseAvinash Backbone Modelers CDE Leaders Vocab Leaders Guides to Mentors TBPT WSCTMS WS IMG WS ICR WS M MM M MMM M M MMM M MM MM M M

Technical Interactions among VCDE WS Participants & ICR WS George DanielaBrianMike FrankDianeDeniseAvinash Backbone Modelers? CDE Leaders Rakesh, Lynne, Dianne R Vocab Leaders? Guides to Mentors Sal, Bob, Baris, Lewis, other Development Projects ICR InteroperabilityElaine/Juli/Subha ICR Working Groups (Issues)

Structure of VCDE WS (continued) Other Activities to Manage Relationship to Compatibility Knowledge Center All Mentoring outside of XC WS Mentoring, Compatibility and Training material Relationship to Vocabulary Knowledge Center Vocabulary services tooling Relationship to Compatibility Service providers Most compatibility reviews in caBIG Other consulting services Relationships to Outside Bodies Other Grids Vocabularies Data Standards Interoperability Software

Implications VCDE WS Leaders will be expected to interact with Domain Workspaces A LOT OUTWARD FACING VCDE WS participants will be expected to set up teleconferences and Centra sessions VCDE WS participants will be expected to take notes, post to Gforge Not all Compatibility reviews, CDE reviews or Vocabulary reviews will be started with a presentation in VCDE WS