Exam please check registrar’s final version of the exam schedule 180 minutes 120 multiple choice questions-120 points -4 short answer question-60 points multiple choice-lecture 7a-12c inclusive short answer-whole term

Note Nutrition 2106-Fall Principles of Nutrition in Metabolism Nutrition 2101-Nutritional Assessment- Theory-Fall 2013 Nutrition Introduction to Sports Nutrition-Winter 2014

Nutrition care plan/essay Due on time please-if problems please ensure I know in advance

Lecture 11a 25 MARCH 2013 Arthritis and Dermatitis

Osteoarthritis (OA) -involves swelling of the joints -overweight – causes wear of cartilaginous surfaces -such wear results in loss of chondroitin sulphate and glucosamine which are carbohydrate polymers

Rheumatoid arthritis (RA) -autoimmune attack that in part involves loss of chondroitin sulphate and glucosamine

Nutrition approaches to Arthritis -appropriate nutrition and exercise may prevent weight gain thus avoiding that cause of osteoarthritis

Nutrition approaches to Arthritis nutraceuticals -chondroitin sulphate -glucosamine -both of these nutraceuticals are meant to replace lost chondroitin sulphate and glucosamine -both readily available over the counter (OTC) and are useless

Nutrition approaches to Arthritis Nutraceuticals -fish oils reduce arachidonic derived pro- inflammatory eicosanoids while producing anti- inflammatory eicosanoids in RA but not OA -evening primrose oil, blackcurrant oil, and borage oil reduce arachidonic derived pro-inflammatory eicosanoids while producing anti-inflammatory eicosanoids in RA but not OA -review pathways involved for nutraceutical oils

Class activity-what is the best nutritional approach to arthritis? Why?

Dermatitis Atopic (eczema) -skin inflammation that is due to an immune response -can be due to a food allergy -solution -avoid food allergen

Dermatitis-nutraceutical -fish oils reduce arachidonic derived pro- inflammatory eicosanoids while producing anti- inflammatory eicosanoids -evening primrose oil and borage oil reduce arachidonic derived pro-inflammatory eicosanoids while producing anti-inflammatory eicosanoids -as with RA many of these trials include subjects that are on anti-inflammatory prescribed drugs- what is the impact of this?

Dermatitis Sebborheic (scaly) -can be due to biotin deficiency avoid biotin deficiency - can be due to riboflavin deficiency avoid riboflavin deficiency

Scaling eczema-like dermatitis -can be due to linoleic or  -linolenic acid deficiency -this may be a problem with long term TPN

Nutritional remedy for dermatitis (types above) in general -topical application of retinoids (similar in structure to vitamin A) -reduces dermatitis -avoid linoleic or  -linolenic acid deficiency

Dermatitis herpetiformis -causes skin lesions pruritic-itching vesicular-vesicles papular-solid elevation of the skin - all of these lesions are consistent with coeliac disease and are relieved by a gluten-free diet