Coronaviruses and Noroviruses Stanley I. Martin, MD Associate Professor Division of Infectious Diseases
Primary objectives 1.Recognize the structure and microbial physiology of Coronaviruses and Noroviruses and integrate this information with the human pathophysiologic correlates 2.Describe physical and chemical properties of Coronaviruses and Noroviruses 3.Describe the replication of Coronaviruses and Noroviruses 4.Describe the underlying genetic mechanisms of Coronaviruses and Noroviruses 5.Recognize the molecular basis of pathogenesis of infections due to Coronaviruses and Noroviruses
Primary objectives 6.Describe the physiology of infections due to Coronaviruses and Noroviruses 7.Identify the normal human immune response to infections due to Coronaviruses and Noroviruses 8.Recognize the epidemiology and ecology of infections due to Coronaviruses and Noroviruses 9.Describe and differentiate the principles of laboratory diagnosis of infections due to Coronaviruses and Noroviruses 10.Describe the treatment, prevention and control of infections due to Coronaviruses and Noroviruses
Coronaviruses
Noroviruses
Normal small bowel mucosa Small bowel mucosa infected by norovirus
Norovirus outbreaks in U.S.,
Diagnosis and treatment
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Primary reference Medical Microbiology, 7 th Ed. Murray, Rosenthal & Pfaller; Chapter 55, pages 506 – 511