Pharmaceutical Dosage Forms

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Presentation transcript:

Pharmaceutical Dosage Forms By S.Bohlooli, PhD School of Medicine, Ardabil University of Medical Sciences

Dosage Form/ Drug Delivery System by route of administration Oral Tablets Capsules Solutions Syrups Elixirs Suspensions Magmas Gels Powders Sublingual Tablets Troches and Lozenges Parenteral Solutions Suspensions Conjunctival Contact lens inserts Ointments

Dosage Form/ Drug Delivery System by route of administration Epicutaneous / transdermal Ointments Creams Infusion pumps Pastes Plasters Powders Aerosols Lotions Transdermal patches, discs, solutions Intraocular/ intraaural Solutions Suspensions Intranasal Sprays Inhalers Ointments Intrarespiratory Aerosols

Dosage Form/ Drug Delivery System by route of administration Vaginal Solutions Ointments Emulsion foams Gels Tablets Inserts, suppositories, sponges Rectal Solutions Ointments Suppositories Urethral suppositories

Powders and Granules Capsules and Tablets Solid Dosage Forms Powders and Granules Capsules and Tablets

Powders and Granules Powders Granules Blending Powders Medicated Powders Aerosolized Powders Granules Effervescent

Capsules Hard Gelatin Capsules Soft Gelatin Capsules

Hard Gelatin Capsules

Tablets Compressed tablets (C.T.) Multiple Compressed tablets (M.C.T.) Sugar-Coated Tablets (S.C.T.) Film Coated Tablets (F.C.T) Gelatin Coated Tablets Enteric Coated Tablets (E.C.T.) Buccal or Sublingual Tablets Chewable Tablets Effervescent Tablets Molded Tablets Immediate release Tablets (I.R.) Instant Disintegrating /Dissolving Tablets Extended release Tablets (E.R.) Vaginal Tablets

Compressed Tablets contains: Medicinal agent Diluents or filler Binders or adhesives Disintergrants Lubricants Miscellaneous adjuncts Colorants and flavorants

Tablets Multiple Compressed tablets Sugar-Coated Tablets Film Coated Tablets Gelatin Coated Tablets Enteric Coated Tablets

Modified-Release Dosage Forms and Drug Delivery Systems Extended Release Delayed Release Repeat action Targeted Release Terminology of extended release Sustained Release (SR) Sustained Action (SA) Prolonged Action (PA) Controlled Release (CR) Extended Release (ER) Timed Release (TR) Long Acting (LA)

Modified-Release Dosage Forms Extended Release

Example of oral control release capsule

Nonoral Modified-Release Systems Ocular Parenteral Systems Vaginal Inserts Subdermal Implants

Ocusert: Pilocarpine Modified Released System

Example of Parenteral extended action products

Example of vaginal extended release products

Example of Subdermal extended release products

Semi-Solid Dosage Forms Ointments Creams Gels Pastes Plasters

Transdermal Drug Delivery Systems

Example Of transdermal Drug delivery systems

Pharmaceutical Inserts Suppositories Inserts

Solutions Disperse systems Liquid Dosage forms Solutions Disperse systems

Solutions Oral Solutions Otic Solutions Ophthalmic Solutions Topical Solutions Spirits

Oral Liquid Dosage Forms Oral solutions Syrups Elixirs Tinctures

Example of Syrup Antihistamine Syrup Chlorpheniramine maleate 0.4g Glycerin 25.0ml Syrup base 83.0 ml Sorbitol solution 283 ml Sodium Bezoate 1.0 g Alcohol 60.0 ml Color and Flavor q.s. Purified water to make 1000.0ml

Example of Elixir Theophylline Elixir Theophylline 5.3 g Citric acid 10.0 g Liquid Glucose 44.0 g Syrup 132 ml Glycerin 50.0 ml Sorbitol Solution 324.0 ml Alcohol 200.0 ml Saccharin Sodium 50 g Lemon Oil 0.5 g FDC Yellow No. 5 0.1 g Purified water to make 1000.0 ml

Disperse Systems Suspensions Emulsions Aerosols

Sterile Dosage Forms and Delivery Systems Parenterals Biologicals Ophthalmic solutions and suspensions

Injection Types

Automatic injection Medi-Jector:Needle Free

Novel and Advanced Dosage Forms, Delivery Systems, and Devices Iontophoresis Phonophoresis Intravenous controllers and infusion pumps, lyposomes

Iontophoresis

Phonophoresis

Intravenous controllers