Neuropeptide Y regulates the hematopoietic stem cell microenvironment and prevents nerve injury in the bone marrow by Min Hee Park, Hee Kyung Jin, Woo ‐ Kie Min, Won Woo Lee, Jeong Eun Lee, Haruhiko Akiyama, Herbert Herzog, Grigori N Enikolopov, Edward H Schuchman, and Jae ‐ sung Bae EMBO J. Volume 34(12): June 12, 2015 ©2015 by European Molecular Biology Organization

NPY deficiency induces impairment of HSC survival in BM Min Hee Park et al. EMBO J. 2015;34: ©2015 by European Molecular Biology Organization

NPY is required for bone marrow regeneration Min Hee Park et al. EMBO J. 2015;34: ©2015 by European Molecular Biology Organization

NPY deficiency causes the reduction of SNS fibers and ECs Min Hee Park et al. EMBO J. 2015;34: ©2015 by European Molecular Biology Organization

Reduction of SNS fibers and ECs is due to p53 ‐ dependent apoptosis Min Hee Park et al. EMBO J. 2015;34: ©2015 by European Molecular Biology Organization

The NPY/Y1 receptor contributes to bone marrow microenvironment cell survival Min Hee Park et al. EMBO J. 2015;34: ©2015 by European Molecular Biology Organization

The NPY/Y1 receptor pathway in macrophages improves bone marrow injury Min Hee Park et al. EMBO J. 2015;34: ©2015 by European Molecular Biology Organization

NPY prevents cisplatin ‐ induced mouse death by restoring bone marrow dysfunction Min Hee Park et al. EMBO J. 2015;34: ©2015 by European Molecular Biology Organization