BRONCHOGENIC CARCINOMA BRONCHOGENIC CARCINOMA, GROSS.

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Presentation transcript:

BRONCHOGENIC CARCINOMA

BRONCHOGENIC CARCINOMA, GROSS

BRONCHOGENIC CARCINOMA

SMALL CELL CARCINOMA

METASTASES IN LUNG

BRONCIOALVEOLAR CELL CARCINOMA

CARCINOMA OF LARYNX

HYALINE MEMBRANE DISEASE

SYSTEMIC HISTIOPLAMOSIS – MACROPHAGES WITH FUNGI

HISTIOPLAMOSIS

Histoplasmosis

PEPTIC ULCER

CARCINOMA OF STOMACH – SIGNET RING CELLS

Signet-ring carcinoma cells from Kumar

CARCINOMA OF STOMACH – SIGNET RING CELLS

CA OF STOMACH METASTATIC TO OVARIES – KRUCKENBERG TUMOR

TUBULAR ADENOMA OF COLON

FAMILIAL ADENOMATOUS POLYPOSIS

ADENOCARCINOMA OF COLON

Colon CA A. Rt Colon B. Left Colon

Adenocarcinoma of Colon

DIVERTICULOSIS OF LARGE INTESTINE

MICRONODULAR CIRRHOSIS

NUTMEG LIVER

HEPATIC CONGESTION

PIGMENT GALLSTONES

Left-cholesterol gallstones Right- pigment gallstones

ISLET CELL TUMOR OF PANCREAS

MALLORY BODIES

Minimal Change Disease - Electron Micrograph EM shows effacement of the foot processes.

MINIMAL CHANGE DISEASE

Membranous Nephropathy Membranous nephropathy is the most frequent cause of the nephrotic syndrome in adults (about 30% of cases). May be idiopathic. May be associated with epithelial neoplasms, infections (esp hepatitis B), SLE, and the use of certain drugs such as gold and penicilamine.

Membranous Nephropathy Membranous Nephropathy is caused by the accumulation of immune complexes within the kidney itself. Immune complexes are deposited in a thickened basement membrane creating a "spike and dome" appearance on electron microscopy.

MEMBRANOUS GLOMERULONEPHRITIS

Acute Nephritic Syndrome The most common cause of the acute nephritic syndrome is poststreptococcal (postinfectious) glomerulonephritis. This is an immune-complex mediated disease, with IgG and C3 seen along the GBMs by IF ("lumpy-bumpy" pattern) and large subepithelial "humps" by EM.

Post streptococcal glomerulonephritis

WIRE LOOP ABNORMALITY IN SLE

SUBENDOCARDIAL IMMUNE COMPLEXES /SLE

WIRE LOOP ABNORMALITY IN SLE

GRANNULAR IMMUNOFLUORESCENCE

LINEAR IMMUNOFLUORESCENCE

SUBEPITHELIAL IMMUNE COMPLEX DEPOSIT IN POSTSTREPTOCOCCAL GLOMERULONEPHRITIS

NODULAR GLOMERULOSCLEROSIS (KW NODULES)

RENAL CELL CARCINOMA

CYTOMEGALO- VIRUS INFECTION

CYTOMEGALOVIRUS INFECTION, KIDNEY Nuclear inclusion body seen with CMV infection. Note the large dark nuclear inclusion body surrounded by a clear halo.

Cytomegalovirus

CYTOMEGALOVIRUS INFECTION

ADULT POLYCYSTIC KIDNEY

INFANTILE POLYCYSTIC KIDNEY

RENAL INFARCT