Computer assisted electroretinogram data acquisition and analysis Nick Balge, Andrew Dias, Whitney Johnson, Dan Jonovic Client Dr. Bikash Pattnaik Advisor Professor Mitch Tyler Computer assisted ERG data acquisition and analysis

Window to the World

The Electroretinogram Electrodes placed on retina Retina stimulated Resultant wave recorded and analyzed Helps study eye, systemic diseases Slow-wave time (ms) Voltage(mV)

Problem Statement Design a computer interface Valve control/liquid exchange Integrate light wheel Data storage

The Lab

Design Constraints Design an interface in LabVIEW to  Control & record light intensity  Integrate solution delivery  Real-time analysis  Export data  Adjust sample duration & number

The current interface The interface Displays graphs in real-time Lacks some functionalities The GUI Looks cluttered Unappealing colors User enters input via keyboard

Design 1: Tweak existing interface Keep existing LabVIEW template Add necessary functionality to back end Slightly modify GUI  More visually pleasing  Better organization

Design 2: GUI Overhaul Simplicity Consistency Familiarity

Design 3: Start from scratch Scrap existing design Choose programming Language Focus on modularity

Decision Matrix Criteria (weight) TweakOverhaulStart over Functionality (30)30 Ease of Use (30)1030 Complexity (20)20100 Aesthetic Appeal (15) 515 Modularity (5)225 Total (100)678780

Future Work Code, code, code Universal Design Testing

Questions?

References Green and Kapousta-Bruneau Evidence that L-APS and D,L-APH can preferentially block cone signals in the rat retina. Visual Neuroscience. 24(1): Matsui, Y et al Electroretinogram b/a wave ratio improvement in central retinal vein obstruction. British Journal of Ophthamology. 78(3): Medline Plus Electroretinography. US National Library of Medicine. Creel, D Clinical Electrophysiology. John Moran Eye Center, University of Utah. Audie Technology Flow Pro Automatic Valve Opener. Ido Perlman The Electroretinogram: ERG. John Morgan Eye Center, University of Utah. AA Kazaryan Functional characteristics of the retina in Glaucoma. Acta Opthalmologica Scandinavia. Vol. 85 Issue s240.