VASOPROLIFERATIVE TUMOURS OF THE RETINA Eye (2003) 17, K Jain, AR Berger, YH Yucil, HD McGowan

CASE 1 64y, white, female ?MM  VA ® 6/52 post-op cataract (uneventful) (L) Laser Rx for retinal tear 5y ago VA: 3/60, 6/12 IOP: 24, 16 ® RAPD (+1) ® shallow subtotal exudative RD+ lipid ® orange elevated mass 1 o’clock (SN)/ Vit.: +++ cells B-scan:  internal reflectivity/ CT: NAD 3/12 after: rubeosis+ vit haemorrhage Rubeotic glaucoma: enucleation Histopathology: proliferation of elongated cells+ vessels, no mitoses, no atypia, glial cell origin (gfap,S-100, vimentin)

CASE 2 67y, healthy Indian male ? MM Floaters MI 12y ago/ ® blunt injury ?haemorrhage ® -9.00D  6/12, (L) –5.00D  6/6 ® fundus: orange grey oval shaped mass+ surface NV+Haem. Between ora-equator, no surrounding vessel tortouosity- dilatation B-scan: no acoustic hollowness, no choroidal excavation base:5x4mm, height: 1.2mm 5y FU: no new symptoms, no change in base, height: 1.9mm  in exudate, haemorrhage, pigmentary changes

CASE 3 30y, healthy male ® floaters 1/12 post blunt trauma+ laser Rx for ? Ret. Tear VA: 6/6 R+L ® : round greenish-yellow exudative raised lesion in IT periphery+ overlying vit haemorrhage B-scan:  internal reflectivity/ solid Rx: Cryo  2/52 post:6/18  ERM  3/12:6/9 FU at 6/12: stable VA/ no complications/ no complaints

COMMENTS VTPR Benign reactive gliovascular proliferation Unilateral/ solitary/ no family history/ older Periphery (IT)/ No dilated feeder-draining vessels Not associated with tumours elsewhere Reddish yellow/ peach coloured Exudation/ haemorrhage Macular oedema/ ERM Rubeosis Diagnosis: clinical, B-scan, POH, Family history

DD 1.Ret. Capillary haemangioma 2.Coats 3.PEHC 4.MM 5.Metastasis 6.Post. scleritis

FU Need periodic FU due to sight threatening complications Post cataract Post trauma

Rx Observation Cryo Laser Plaque radiotherapy PDT Thermotherapy TPPV for TRD-ERM Trans-scleral resection Macular pucker: improves sponaneously, delay vity for at least 3/12 after cryo