Endoluminal Closure Device January 25, 2006 Braham Dhillon Ali Hales Laura Mattaliano John Sticklen

Problem Statement: Close Gastrotomy Incision

NOTES: Natural Orifice Transluminal Endoscopic Surgery  Using an endoscope, create a gastrotomy to gain access to peritoneal cavity to perform surgery

Endoscope Port – our device would exit through here

Design Parameters  Incision  Length: 2 cm  Stomach wall thickness: 3-5 mm  Heal within 7-14 days  Endoscope  Port Diameter: 3-4 mm  Length: Varies, depending on scope

Nitinol  Mixture of nickel and titanium  Thermal Shape Memory  Shape dependent on temperature  Biocompatibility  Several FDA approved devices  High corrosion resistance  Intermetallic, not an alloy  Bonding force between nickel and titanium strong  Elastic Deployment  Pass through narrow canal  Return to original shape

Current Design Ideas: Nitinol Coil

Current Designs Ideas: Suturing Mechanism (based on Bard EndoCinch Suturing System)

Current Design Ideas: “Dhillon’s Grab & Pull”

Current Accomplishments  Dr. Attwell  Observation of 2 endoscopic procedures  Colonoscopy  Endoscopic exploratory procedure  Gained better understanding of surgical parameters  Generated ideas for design  CAD drawings of endoscope  Research into potential materials and costs  Nitinol  Thermoplastic Polymer

Current Plan  Determine Final Budget  Decide Final Design, Develop prototype  Materials  Exact Dimensions  GI Mentor  Dr. Caroline Cao  Virtual reality program, simulates gastrointestinal system  Still discussing appointment times

Future Plans  Develop functioning prototype  Ordering Necessary materials  Requesting access to necessary equipment  Determine methods of testing procedure - Materials with properties of stomach - Testing on animal stomachs

Questions?

References   ntroi.stanford.edu  inch.html inch.html inch.html