Klaus F. Rabe MD, PhD and the Challenges of Chronic Respiratory Disease...

Rate per population Heart Disease Cancer Year of Death Stroke Jemal A. et al. JAMA 2005; 294: % -63% -2.7%

Year of Death Accidents Chronic Obstructive Pulmonary Disease Diabetes Jemal A. et al. JAMA 2008; 294: % +100% +3%

Global Alliance against Chronic Respiratory Diseases DiseasePrevalence Asthma300 million COPD210 million Allergic rhinitis400 million Sleep apnea>100 million Others>50 million Everyone in the world is exposed to CRD risk factors often common with other NCDs Co-morbidities - paramount importance - often common with other NCDs Global challenges

POPULATION IMBALANCES IN 2025

SEVERE INCOME DISPARITY IS SEEN TO BE THE NUMBER 1 GLOBAL RISK OVER NEXT 10 YEARS

GLOBAL SNAPSHOT OF INEQUALITY

OECD AREA For every 0.05 increase in Gini coefficient of income inequality, mortality increased 7.8%, with an estimated 1.5 million excess deaths each year in 30 countries in the OECD.

LESS WEALTH MEANS LESS HEALTH Source: Wilkinson and Pickett, The Spirit Level (2009)

HEALTH INEQUALITY IN THE UK

FP7 Health research i.e. € 6 billion (11%) FP7 Respiratory research (4.3%) i.e. € 261 million COPD & asthma research (0.5%) i.e. € 31 million FP7 TOTAL: € 54 BILLION FP7 HEALTH RESEARCH:€ 6 BILLION (11%) EU 7 th Framework Programme (FP7)

–Focus on 4 major NCDs: cardiovascular, respiratory, cancer & diabetes –Implementing the “Political Declaration” adopted at the UN HLM on NCDs (19-20 Sep) “We now have a unique opportunity to take action on chronic respiratory disease and we need to raise maximum awareness. I hope that ERS members from across the world will join me in pressing the UN agencies, WHO and governments to ensure they meet the ambitious commitments made in the Political Declaration to prevent and control NCDs.” – Y. Sibille