CHROMATOGRAPHY 1Biochemistry of Medics. Chromatography 2Biochemistry of Medics.

Slides:



Advertisements
Similar presentations
Size Exclusion Chromatography
Advertisements

Separation of molecules and determination of there molecular weight by gel filtration chromatography. Experiment 7 BCH 333.
Paper and Thin layer Chromatography
Chromatography.
Chromatography Russian scientist Tswett in 1906 used a glass columns packed with finely divided CaCO3 to separate plant pigments extracted by hexane. The.
Gel Filtration Chromatography.
Basics of Chromatography Jony Mallik. Introductory Principles Chromatography is a combination of two words; * Chromo – Meaning color * Graphy – representation.
Chapter 4-1 Chromatography
Separation of Chemical Mixtures Dr. Ron Rusay Spring 2004 © Copyright 2004 R.J. Rusay.
Types of Mechanism in the Chromatography
Magnet Analytical Chemistry Unit 4
Intro to Chromatography
Partition Chromatography It is also known as Liquid-Liquid Chromatography (LLC). If the mobile phrase is gas then it is called Gas-liquid Chromatography.
Chemistry 1- Separation Objectives: 1) Learn about 2 different separation methods.
CHROMATOGRAPHY (DEMONSTRATION) Mrs. Chaitali Maitra
Paper and Thin Layer Chromatography (TLC) Experiment 6 BCH 333 [practical]
CHROMATOGRAPHY. A process to separate molecules to purify them.
DOWNSTREAM PROCESSING
0 Chromatography is a method of physically separating mixtures of gases, liquids, or dissolved substances. Chromatography can be used to identify drugs,
Chapter 23 An Introduction to Analytical Separations.
INTRODUCTION TO CHROMATOGRAPHY DR. Harrizul Rivai, m.s.
- based on selective non-covalent interaction between an analyte and specific molecules. - is often used in biochemistry in the purification of proteins.
Ch 21 – Principles of Chromatography and Mass Spectrometry Ch 22 – Gas and Liquid Chromatography.
Biotechnology: Science for the New Millennium Lab 9c Using Ion Exchange Chromatography to Separate Proteins Ellyn Daugherty SMBCP, San Mateo CA
I NTRODUCTION TO C HROMATOGRAPHY PHR 310: P HARMACEUTICAL A NALYSIS - II.
ADSORPTION CHROMATOGRAPHY
Principles of chromatography
Dr.Leezum Foning Lepcha. Chromatography Chromatography (from Greek chroma "color and graphein "to write") is the collective term for a set of laboratory.
 Laboratory technique for the Separation of mixtures  Chroma -"color" and graphein - "to write”.  Colour bands - separation of individual compounds.
Chromatography. Chromatography is a method of the separation of mixtures based on different affinity of the components of a mixture toward the stationary.
and Identification by Thin-Layer Chromatography
Biochemical instrumental analysis - 9 Dr. Maha Al-Sedik 2016 CLS 332.
CHROMATOGRAPHY.
High Performance Liquid Chromatography. What is HPLC ? It is a separation technique that involves: Injection of small volume of liquid sample Into a tube.
Bioseparation II Chromatography Techniques. Chromatography Most widely used purification technique used for biomolecules. Most widely used purification.
Chromatography 1 Lecture 10 An introduction. What is CHROMATOGRAPHY ? Chromato g raphy.
Dr. Tahir Ali RIPS Riphah International University
BCH BIOCHEMICAL METHODS (2 UNITS) DR AKINLOYE’S ASPECT
Purification Of Proteins.
Purification of Green Fluorescent Protein
Affinity Chromatography By: Ayesha Naeem
LU 3: Separation Techniques
Chromatography The chromatography is discovered by a botanist called Tswett in 1906 when he tried to separate the constituents of a herbal extract by using.
Column Chromatography
Gel Filtration Chromatography.
Basics of Chromatography
Week 6 Chromatography introduction
What is Chromatography?
What is Chromatography?
Biophysical Tools '04 - Chromatography
Techniques of protein purification
Dnyanasadhana College, Thane. Department of Chemistry T. Y. B. Sc
SEPARATION TECHNIQUES
Paper and Thin Layer Chromatography (TLC)
What is Chromatography?
Chapter: Chromatography
Satish Pradhan Dnyanasadhana College, Thane (W)
Gel Filtration Chromatography.
Chromatography Definition Introduction
Last class Salting out Dialysis Paper 1 discussion.
Principle of separation of different components:
Chapter: Chromatography
Satish Pradhan Dnyanasadhana College, Thane. Department of Chemistry T
What is Chromatography?
CHROMATOGRAPHY Presented by Mr.Halavath Ramesh M.A,M.sc,B.ED,PGDCAQM,PGDCA,M.Phil,(P.HD)(UoH) University of Madras Dept.
What is Chromatography?
High-Performance Liquid Chromatography
M.S COLLEGE OF ARTS, SCIENCE, COMMERCE AND B.M.S
Purification of Green Fluorescent Protein
High-Performance Liquid Chromatography
Presentation transcript:

CHROMATOGRAPHY 1Biochemistry of Medics

Chromatography 2Biochemistry of Medics

Chromatography 3Biochemistry of Medics

Chromatography- Principle 4Biochemistry of Medics

Chromatography- Classification 5Biochemistry of Medics

Chromatography- Classification(Contd.) 6Biochemistry of Medics

Partition Chromatography 7Biochemistry of Medics

Paper chromatography 8Biochemistry of Medics

Paper chromatography 9Biochemistry of Medics

Paper chromatography- Procedure 10Biochemistry of Medics

Paper chromatography- Procedure 11Biochemistry of Medics

Ascending and Descending Paper Chromatography 12Biochemistry of Medics

Paper Chromatography -Analysis 13Biochemistry of Medics

R ƒ value 14Biochemistry of Medics

Two dimensional chromatography 15Biochemistry of Medics

Significance of Paper chromatography 16Biochemistry of Medics

Thin layer chromatography (TLC) 17Biochemistry of Medics

TLC- Procedure 18Biochemistry of Medics

TLC -Overview 19Biochemistry of Medics

Significance of TLC 20Biochemistry of Medics

Advantages of TLC over paper chromatography 21Biochemistry of Medics

2)Adsorption chromatography 22Biochemistry of Medics

2)Adsorption chromatography- Elution 23Biochemistry of Medics

Adsorption chromatography The substance loosely adsorbed to the stationary medium comes in the earlier fraction. 24Biochemistry of Medics

Ion – Exchange chromatography 25Biochemistry of Medics

Ion – Exchange chromatography 26Biochemistry of Medics

Ion – Exchange chromatography- Procedure 27Biochemistry of Medics

Ion – Exchange chromatography- Procedure (Contd.) 28Biochemistry of Medics

Types of ion exchanges resins 29Biochemistry of Medics

Ion – Exchange chromatography- An Overview 30Biochemistry of Medics

4) Gel filtration chromatography or Molecular Sieve chromatography 31Biochemistry of Medics

Gel filtration chromatography or Molecular Sieve chromatography 32Biochemistry of Medics

Gel filtration chromatography-An Overview Larger particles come out first, while smaller particles come in later fractions 33Biochemistry of Medics

5) Affinity chromatography 34Biochemistry of Medics

Affinity chromatography- Significance 35Biochemistry of Medics

Affinity chromatography- Significance By using antibodies, antigens can be easily separated. Conversely, antibodies can be purified by passing through a column containing the antigen. Specific Antibody binds to a specific antigen attached to the stationary medium, the remaining antibodies come out in earlier fractions. 36 Biochemistry of Medics

6) High performance liquid chromatography- 37Biochemistry of Medics

High performance liquid chromatography- 38Biochemistry of Medics

High performance liquid chromatography- Significance 39Biochemistry of Medics

High performance liquid chromatography- Apparatus 40Biochemistry of Medics

6) Gas liquid chromatography- 41Biochemistry of Medics

Gas liquid chromatography- 42Biochemistry of Medics

Gas liquid chromatography-Apparatus 43Biochemistry of Medics

Summary 44Biochemistry of Medics