Klinefelter’s? Syndrome? Klinefelter’s? Syndrome? Klinefelter’s? Syndrome? Klinefelter’s? Syndrome? Klinefelter’s?

Chromosomal disorder

1 every 550 males

Chromosomal disorder 1 every 550 males Additional X chromosome

Chromosomal disorder 1 every 550 males Additional X chromosome 47 XXY pair

Chromosomal disorder 1 every 550 males Additional X chromosome 47 XXY pair TESTES

Chromosomal disorder 1 every 550 males Additional X chromosome 47 XXY pair TESTES Don’t make enough testosterone

Chromosomal disorder 1 every 550 males Additional X chromosome 47 XXY pair TESTES Don’t make enough testosterone Don’t make any sperm

Chromosomal disorder 1 every 550 males Additional X chromosome 47 XXY pair TESTES Don’t make enough testosterone Don’t make any sperm Learning difficulties

Chromosomal disorder 1 every 550 males Additional X chromosome 47 XXY pair TESTES Don’t make enough testosterone Don’t make any sperm Learning difficulties Behavior difficulties

Chromosomal disorder 1 every 550 males Additional X chromosome 47 XXY pair TESTES Don’t make enough testosterone Don’t make any sperm Learning difficulties Behavior difficulties 3/10 diagnosed forever

Chromosomal disorder 1 every 550 males Additional X chromosome 47 XXY pair TESTES Don’t make enough testosterone Don’t make any sperm Learning difficulties Behavior difficulties 3/10 diagnosed forever Small testes

Chromosomal disorder 1 every 550 males Additional X chromosome 47 XXY pair TESTES Don’t make enough testosterone Don’t make any sperm Learning difficulties Behavior difficulties 3/10 diagnosed forever Small testes Need for testosterone replacement

Chromosomal disorder 1 every 550 males Additional X chromosome 47 XXY pair TESTES Don’t make enough testosterone Don’t make any sperm Learning difficulties Behavior difficulties 3/10 diagnosed forever Small testes Need for testosterone replacement Gel on skin or injection

Chromosomal disorder 1 every 550 males Additional X chromosome 47 XXY pair TESTES Don’t make enough testosterone Don’t make any sperm Learning difficulties Behavior difficulties 3/10 diagnosed forever Small testes Need for testosterone replacement Gel on skin or injection Muscle strength

Chromosomal disorder 1 every 550 males Additional X chromosome 47 XXY pair TESTES Don’t make enough testosterone Don’t make any sperm Learning difficulties Behavior difficulties 3/10 diagnosed forever Small testes Need for testosterone replacement Gel on skin or injection Muscle strength Body hair

Chromosomal disorder 1 every 550 males Additional X chromosome 47 XXY pair TESTES Don’t make enough testosterone Don’t make any sperm Learning difficulties Behavior difficulties 3/10 diagnosed forever Small testes Need for testosterone replacement Gel on skin or injection Muscle strength Body hair Strong bones

Chromosomal disorder 1 every 550 males Additional X chromosome 47 XXY pair TESTES Don’t make enough testosterone Don’t make any sperm Learning difficulties Behavior difficulties 3/10 diagnosed forever Small testes Need for testosterone replacement Gel on skin or injection Muscle strength Body hair Strong bones Less fat

Chromosomal disorder 1 every 550 males Additional X chromosome 47 XXY pair TESTES Don’t make enough testosterone Don’t make any sperm Learning difficulties Behavior difficulties 3/10 diagnosed forever Small testes Need for testosterone replacement Gel on skin or injection Muscle strength Body hair Strong bones Less fat INFERTILITY

Only the few...