Pathogenesis beyond the cancer clone(s) in multiple myeloma by Giada Bianchi, and Nikhil C. Munshi Blood Volume 125(20):3049-3058 May 14, 2015 ©2015 by.

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Pathogenesis beyond the cancer clone(s) in multiple myeloma by Giada Bianchi, and Nikhil C. Munshi Blood Volume 125(20): May 14, 2015 ©2015 by American Society of Hematology

Pathogenesis of MM. The orange round cell represents a normal B cell, whereas the yellow round cell is a mutated, post–germinal center (GC) B lymphocyte that later differentiates into a long-lived PC (yellow oval). Giada Bianchi, and Nikhil C. Munshi Blood 2015;125: ©2015 by American Society of Hematology

Role of the BM niche in MM pathogenesis. Giada Bianchi, and Nikhil C. Munshi Blood 2015;125: ©2015 by American Society of Hematology