Suppression of inflammatory and neuropathic pain symptoms in mice lacking the N ‐ type Ca 2+ channel by Hironao Saegusa, Takashi Kurihara, Shuqin Zong, An ‐ a Kazuno, Yoshihiro Matsuda, Takahiro Nonaka, Wenhua Han, Hideyuki Toriyama, and Tsutomu Tanabe EMBO J. Volume 20(10): May 15, 2001 ©2001 by European Molecular Biology Organization

Generation of mice lacking the α12.2 subunit of the N ‐ type VDCC. (A) A simplified restriction map around exon 1 of the Cacna1b gene and structure of the targeting vector. Hironao Saegusa et al. EMBO J. 2001;20: ©2001 by European Molecular Biology Organization

Ba2+ currents in DRG neurons from Cav2.2+/+ and Cav2.2−/− mice and effects of toxins on the Ba2+ currents. Hironao Saegusa et al. EMBO J. 2001;20: ©2001 by European Molecular Biology Organization

Anxiety ‐ related behaviors of wild ‐ type (+/+), heterozygote (+/−) and homozygous mutant mice (−/−). Hironao Saegusa et al. EMBO J. 2001;20: ©2001 by European Molecular Biology Organization

Acute nociceptive responses of wild ‐ type (+/+), heterozygote (+/−) and homozygous mutant mice (−/−). Hironao Saegusa et al. EMBO J. 2001;20: ©2001 by European Molecular Biology Organization

Nociceptive responses to noxious chemical stimulation of cutaneous or visceral tissue. Hironao Saegusa et al. EMBO J. 2001;20: ©2001 by European Molecular Biology Organization

Mechanical allodynia and thermal hyperalgesia induced by spinal nerve ligation. Hironao Saegusa et al. EMBO J. 2001;20: ©2001 by European Molecular Biology Organization