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 Reading:  Chapter 21  Chapter 8  Discussion Board  Seminar  Assignment

The endocrine system regulates the body’s homeostasis. Principal glands of the endocrine system: Hypothalmus-pituitary Thyroid Parathyroid Pancreas Adrenals Ovary Testes

 Gland located in neck that sequesters iodine from the bloodstream.  Release of thyroid hormones (T4 and T3) is regulated by thyroid- stimulating factor (TSH), which is released by the anterior pituitary.  Thyroxine (T 4 ) accelerates metabolism.  Iodine couples to thyroid hormones.

 Most common disorder of the thyroid gland.  Failure of thyroid to produce sufficient thyroid hormone is the primary cause.  Treatment is the replacement of thyroid hormone, primarily T4 (levothyroxine, Synthroid®).  What is some patient education on hypothyroidism and therapy? (p. 412 of textbook)

Turn to p. 123 of the workbook. As a class, let’s discuss Scenario 1.

7 Pancreatic beta cells produce the hormone insulin. Insulin helps transport glucose into cells to be broken down into energy. Diabetes = low insulin and high blood glucose.

 Type 1:  Juvenile-onset  Inadequate production of insulin  Autoimmune disease that kills beta cells in the pancreas  Underweight  If untreated, body starves because glucose cannot gain access into key body organs  Type 2:  Adult-onset  “Relative” lack of insulin production  Genetic

9  Let’s discuss the different types of insulin products. (p. 421 of textbook)  What are some drugs that interact with insulin? (p. 427 of textbook) (p. 427 of textbook)

10 Rules: I will provide a clue, and you respond with a question that corresponds to that clue. Example: Clue: “Pancreas” Student Response: “What is the organ that secretes insulin?

 Refer to Chapters 7, 8 and 9.  Turn in early in case you need to make corrections.  Don’t forget about the Math Center if you need help. 11

12 Ratio —expression comparing two quantities ◦ separated by colon or written as fraction (1:3 or 1/3) Proportion —comparing two fractions (ratios) considered to be equal ◦ 1:2 and 2:4 same as 1/2 = 2/4

 Example:  Ordered: 5 mg po tid  On hand: 2 mg scored tablets  How many tablets do you need for each dose?

 Example:  Ordered: 200 mg po q8h  On hand: 125mg/5 mL  How many mL’s do you need for each dose?

 Example :  Ordered: 1.5 g  On hand: 15 mg/mL  How many mL’s do you need to give the ordered amount?

 Example:  Ordered: 120 mL  On hand: tsp  How many tsp’s do you need to give the ordered amount?

 Thank you for your attention and participation in tonight’s seminar!  Any questions?  I look forward to the rest of Unit 7. Please contact me with any questions throughout the week.