Biohazardous proceses Contained laboratory Unloading area Autoclave chamber Air Sources of contamination Technical area Condensates Leaks

Safety systems Contained laboratory Unloading area Autoclave chamber Air Basic securities (user’s level) SPF flange (Bioseal) Filter Venting (air) filter Technical area Condensates

Safety systems Contained laboratory Unloading area Technical area Autoclave chamber Condensates Air Basic securities (user’s and environment level) SPF flange (Bioseal) Filter Venting (air) filter BioWaste BioWaste (tank, digestor, etc.)

Contained laboratory Unloading area Autoclave Air Total security for user’s and environment with Hi-Ri design SPF flange (Bioseal) Filter Venting (air) filter Technical area Hi-Ri design (option) Condensates HI-RI Safety systems

User’s requirements for High Risk biological processing SPF flange or Bioseal, either in one or both sides Air exhaust absolute filter Basic requirements Condensates to BioWaste Non contaminated watersto drainage Condensates retention and steam inlet through drainage With our HI-RI design option Extra securities to be assessed: Steam barrier, steam to door gasket, dual temperature probes, etc. Control through chamber temperature probe instead of drain temperature SPF flange or Bioseal, either in one or both sides Vacuum and air exhaust through absolute filter

P&ID - Bio HI-RI design

Vacuum pulses

Pressure pulses

Steaming

Chamber steaming

Chamber and filter steaming

Filter drying

Sterilisation

Cooling

Cycle end

Instrumentación