Nuclear Reprogramming in Cells by J. B. Gurdon, and D. A. Melton Science Volume 322(5909): December 19, 2008 Published by AAAS

Fig. 1. Designs of nuclear transfer experiments (A) to unfertilized eggs (second meiotic metaphase) of frogs or mammals or (B) to first meiotic frog oocytes. J. B. Gurdon, and D. A. Melton Science 2008;322: Published by AAAS

Fig. 2. Nuclear transfer success decreases as donor cells differentiate (3, 8). J. B. Gurdon, and D. A. Melton Science 2008;322: Published by AAAS

Fig. 3. Nuclei enlarge and chromatin decondenses during nuclear reprogramming. J. B. Gurdon, and D. A. Melton Science 2008;322: Published by AAAS

Fig. 4. Chromosomal protein exchange in a normal cell (left) or after nuclear transfer to an egg or oocyte (right). J. B. Gurdon, and D. A. Melton Science 2008;322: Published by AAAS

Fig. 5. Four experimental routes for nuclear reprogramming. J. B. Gurdon, and D. A. Melton Science 2008;322: Published by AAAS