The Brain and Behavior Outline Functions Evolution: structure and behavior Basic Unit: The Neuron Generation: How does a signal get started? Action Potential: How does a signal move? Synapses Reflexes: A model Brain Organizing Principles and Functions
Functions Communication Coordination Control Cognition Complexity
Outline: Start With A Mechanistic View Functions Evolution: structure and behavior Basic Unit: The Neuron Generation: How does a signal get started? Action Potential: How does a signal move? Synapses Reflexes: A model Brain Organizing Principles and Functions
Evolution None Nerve net Segmented Cephalization: an organizing principle (brain- mind correlation not always obvious!) Kineses Taxes Reflexes
Evolution
Brain Structure
DRUGS
Evolution None Nerve net Segmented Cephalization: an organizing principle (brain-mind correlation not always obvious!) Kineses Taxes Reflexes
Kinesis (potato bug) Taxis (moth / maggot / fly / tick) Reflex: (knee jerk) –Descartes 161 St. Germaine on the Seine –Pineal –Mechanist
Reflexes Braightenberg: Vehicles
Outline Functions Evolution: structure and behavior Basic Unit: The Neuron Generation: How does a signal get started? Action Potential: How does a signal move? Synapses Reflexes: A model Brain Organizing Principles and Functions
The Neuron 100 billion Varied in size, shape, function Function of neuron sending signals in real time (ex.) What is the signal? - electrical / chemical
Outline Functions Evolution: structure and behavior Basic Unit: The Neuron Generation: How does a signal get started? Action Potential: How does a signal move? Synapses Reflexes: A model Brain Organizing Principles and Functions
Origin of nerve signal Function of neuron sending signals in real time (ex.) What is the signal? - electrical / chemical
Generation Two forces: –Electrical (ionic) –Chemical (concentration) –Give rise to steady-state voltage “resting potential” –Universal in cells
Outline Functions Evolution: structure and behavior Basic Unit: The Neuron Generation: How does a signal get started? Action Potential: How does a signal move? Synapses Reflexes: A model Brain Organizing Principles and Functions
Action Potential
Movement of a Signal
Action Potential Cell actions Speed: Muller (light), Helmholtz (43 m/sec) Refractoriness All or none law Coding of intensity: analog-digital + recruitment (organizing principle)
Neuron Communication Propagation is much faster if the axon is myelinated: Depolarization proceeds down the axon by a number of skips or jumps. The action potential obeys the all-or- none law: Once it’s launched, further increases in stimulus intensity have no effect on its magnitude.
Neuron Communication Propagation is much faster if the axon is myelinated: Depolarization proceeds down the axon by a number of skips or jumps. The action potential obeys the all-or- none law: Once it’s launched, further increases in stimulus intensity have no effect on its magnitude. Frequency signals intensity
Outline Functions Evolution: structure and behavior Basic Unit: The Neuron Generation: How does a signal get started? Action Potential: How does a signal move? Synapses Reflexes: A model Brain Organizing Principles and Functions
Synapses: What happens when signal reaches end of neuron? Two types of actions - excitatory / inhibitory Chemical model Temporal & spatial summation
Synapses
Release of Neurotransmitter
Synapses
Outline Functions Evolution: structure and behavior Basic Unit: The Neuron Generation: How does a signal get started? Action Potential: How does a signal move? Synapses Reflexes: A model Brain Organizing Principles and Functions
A Model for building behavior out of simple building blocks Reflexes Voting behavior Mirror neurons Other examples to follow
Reflexes: A model
Outline Functions Evolution: structure and behavior Basic Unit: The Neuron Generation: How does a signal get started? Action Potential: How does a signal move? Synapses Reflexes: A model Brain Organizing Principles and Functions
Principles and Functions Cephalization All-or-None Law Frequency Coding of Intensity Doctrine of Specific Nerve Energies Localization of Function (+ Integration) Topographic Projection (& Distortion) Split Brain (Crossed Connections) Connectivity & Functional Connectivity Neuro-plasticity & Reorganization
Brain Structure (midline)
Structure: Central Core
Structure: X-Ray View
Localization of Function
Localization/Topographic Projection
Localization/Topographic Proj.
Split Brain