Who Are the Long-QT Syndrome Patients Who Receive an Implantable Cardioverter-Defibrillator and What Happens to Them?Clinical Perspective by Peter J. Schwartz,

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Presentation transcript:

Who Are the Long-QT Syndrome Patients Who Receive an Implantable Cardioverter-Defibrillator and What Happens to Them?Clinical Perspective by Peter J. Schwartz, Carla Spazzolini, Silvia G. Priori, Lia Crotti, Alessandro Vicentini, Maurizio Landolina, Maurizio Gasparini, Arthur A.M. Wilde, Reinoud E. Knops, Isabelle Denjoy, Lauri Toivonen, Gerold Mönnig, Majid Al-Fayyadh, Luc Jordaens, Martin Borggrefe, Christina Holmgren, Pedro Brugada, Luc De Roy, Stefan H. Hohnloser, and Paul A. Brink Circulation Volume 122(13): September 28, 2010 Copyright © American Heart Association, Inc. All rights reserved.

Pre-ICD history of cardiac events according to genotype. Peter J. Schwartz et al. Circulation. 2010;122: Copyright © American Heart Association, Inc. All rights reserved.

Distribution of patients at implantation by age and gender. Peter J. Schwartz et al. Circulation. 2010;122: Copyright © American Heart Association, Inc. All rights reserved.

Cumulative event-free survival for a first appropriate ICD shock in the study population. Peter J. Schwartz et al. Circulation. 2010;122: Copyright © American Heart Association, Inc. All rights reserved.

Cumulative event-free survival for a first appropriate ICD shock according to a prior ACA on or off therapy. Peter J. Schwartz et al. Circulation. 2010;122: Copyright © American Heart Association, Inc. All rights reserved.

A, Cumulative event-free survival for a first appropriate ICD shock according to a prior history of syncope on or off therapy. Peter J. Schwartz et al. Circulation. 2010;122: Copyright © American Heart Association, Inc. All rights reserved.

Cumulative event-free survival for a first appropriate ICD shock according to genotype. Peter J. Schwartz et al. Circulation. 2010;122: Copyright © American Heart Association, Inc. All rights reserved.

Cumulative event-free survival for a first appropriate ICD shock according to an increasing risk score in (A) all patients and (B) patients with no prior ACA. Peter J. Schwartz et al. Circulation. 2010;122: Copyright © American Heart Association, Inc. All rights reserved.