1 |1 | Countries using and planning to introduce IPV and the global status of bOPV registration Countries using and planning to introduce IPV and the global status of bOPV registration

2 |2 | Countries using and planning to introduce IPV August 2016 status report This slide deck provides a summary per country on the status of planning for the introduction of Inactivated Poliomyelitis Vaccine (IPV). It also includes a summary of the global status of national registration of bivalent Oral Polio Vaccine (bOPV), in preparation for the switch from trivalent OPV (tOPV) to bOPV. Information here is updated monthly based on information shared by WHO and UNICEF Regional Offices. Please contact with any questions or updates on this Definitions Formal decision to introduce: The country has documentation of its decision to introduce IPV which has been verified by the relevant WHO Regional Office, or for Gavi eligible countries, a complete application for IPV has been submitted to the Gavi Secretariat. Tracking these decisions and informal intents provide an indication of the global trend towards meeting the targets of the Polio Eradication and Endgame Strategic Plan.

3 |3 | Countries using IPV vaccine to date and formal decision to introduce Data source: WHO/IVB Database, as of 03 August 2016 Map production Immunization Vaccines and Biologicals (IVB), World Health Organization Date of slide: 3 August 2016 The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. ©WHO All rights reserved. Introduced* to date (172 countries or 89%) Formal commitment to introduce in August 2016 (2 countries or 1%) Introduction delayed to December 2017 (20 countries or 10%) Not available Not applicable Since January 2013, the following countries have introduced IPV: Kazakhstan, Peru & Singapore (July 2013); Micronesia (August 2013); Libya (April 2014); Albania & Panama (May 2014); Nepal & Tunisia (September 2014); Philippines (October 2014); China (December 2014); Comoros, Senegal & Serbia (January 2015); Colombia & Nigeria (February 2015); Bangladesh & Maldives (March 2015); DR Congo, DPR Korea & The Gambia (April 2015); Madagascar (May 2015); Cote d'Ivoire, Grenada, Kiribati, Morocco, St Vincent and the Grenadines & Sudan (June 2015); Bhutan, Cameroon, Niger, Pakistan, Philippines & Sri Lanka (July 2015); Benin, Chad, Papua New Guinea, The Former Yug. Rep. of Macedonia (August 2015); Afghanistan, CAR, Dominica, Guyana, Iran, Jamaica, Seychelles & Solomon Islands (September 2015); Bahamas, Lao People's Dem Rep, Nauru, Samoa (October 2015); Antigua and Barbuda, Botswana, Burundi, Cook Islands, Guinea, India, Mauritania, Mauritius, Mozambique, Namibia, Nicaragua, St Lucia, Suriname, Tuvalu, Vanuatu & Yemen (November 2015); Algeria, Belize, Cambodia, Dominical Rep, Ecuador, Ethiopia, Fiji, Gabon, Georgia, Honduras, Kenya, Myanmar, Paraguay, St Kitts & Nevis, S. Sudan, Thailand, Tonga & Trinidad & Tobago (December 2015); Cuba, El Salvador, Guatemala, Haiti, Iraq & Venezuela (Bolivian Rep of) (January 2016); Azerbaijan, Bolivia & Timor-Leste (February 2016); Chile & Mali (March 2016); Argentina, Congo, Djibouti, Lesotho, Sao Tome & P., Uganda (April 2016); Armenia, Guinea-Bissau, Indonesia & Swaziland (July 2016) * Including partial introduction in India

4 |4 | Countries using IPV vaccine to date and introductions planned according to Gavi eligibility status Date of slide: 3 August 2016 The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. ©WHO All rights reserved. Since January 2013, the following countries have introduced IPV: Kazakhstan, Peru & Singapore (July 2013); Micronesia (August 2013); Libya (April 2014); Albania & Panama (May 2014); Nepal & Tunisia (September 2014); Philippines (October 2014); China (December 2014); Comoros, Senegal & Serbia (January 2015); Colombia & Nigeria (February 2015); Bangladesh & Maldives (March 2015); DR Congo, DPR Korea & The Gambia (April 2015); Madagascar (May 2015); Cote d'Ivoire, Grenada, Kiribati, Morocco, St Vincent and the Grenadines & Sudan (June 2015); Bhutan, Cameroon, Niger, Pakistan, Philippines & Sri Lanka (July 2015); Benin, Chad, Papua New Guinea, The Former Yug. Rep. of Macedonia (August 2015); Afghanistan, CAR, Dominica, Guyana, Iran, Jamaica, Seychelles & Solomon Islands (September 2015); Bahamas, Lao People's Dem Rep, Nauru, Samoa (October 2015); Antigua and Barbuda, Botswana, Burundi, Cook Islands, Guinea, India, Mauritania, Mauritius, Mozambique, Namibia, Nicaragua, St Lucia, Suriname, Tuvalu, Vanuatu & Yemen (November 2015); Algeria, Belize, Cambodia, Dominical Rep, Ecuador, Ethiopia, Fiji, Gabon, Georgia, Honduras, Kenya, Myanmar, Paraguay, St Kitts & Nevis, S. Sudan, Thailand, Tonga & Trinidad & Tobago (December 2015); Cuba, El Salvador, Guatemala, Haiti, Iraq & Venezuela (Bolivian Rep of) (January 2016); Azerbaijan, Bolivia & Timor-Leste (February 2016); Chile & Mali (March 2016); Argentina, Congo, Djibouti, Lesotho, Sao Tome & P., Uganda (April 2016); Armenia, Guinea-Bissau, Indonesia & Swaziland (July 2016) Data source: WHO/IVB Database, as of 03 August 2016 Map production Immunization Vaccines and Biologicals (IVB), World Health Organization * Including partial introduction in India Gavi countries with formal commitment to introduce in (18 countries or 9%) Not available Not applicable Introduced to date* (172 countries or 89%) Non Gavi countries with formal commitment to introduce in (4 countries or 2%)

5 |5 | 22 countries introducing IPV between 3 August 2016 and December 2017 Tier 1 countries are countries with cVDPV2 transmission or cVDPV2 reported since 2000 & WPV endemic countries Tier 2 countries are countries with cVDPV 1/3 since 2000 or large /medium size countries with DTP3 coverage <80% in the past 3 years as per WUENIC Data source: WHO/IVB Database, as of 03 August 2016 Map production Immunization Vaccines and Biologicals (IVB), World Health Organization Aug-16Dec-17 Cabo VerdeAngola Equatorial GuineaBurkina Faso Egypt Eritrea Ghana Kyrgyzstan Liberia Malawi Mongolia Rep. of Moldova Rwanda Sierra Leone Tajikistan Togo Turkmenistan United Rep. of Tanzania Uzbekistan Viet Nam Zambia Zimbabwe 220 Legend Tier 2 countries

6 |6 | Tier 1 and 2 Countries using IPV vaccine to date and formal decision to introduce Tier 1 countries are countries with cVDPV2 transmission or cVDPV2 reported since 2000 & WPV endemic countries Tier 2 countries are countries with cVDPV 1/3 since 2000 or large /Medium size countries with DTP3 coverage <80% in the past 3 years as per WUENIC Data source: WHO/IVB Database, as of 03 August 2016, based on 36 tier 1 & 2 countries Map production Immunization Vaccines and Biologicals (IVB), World Health Organization Date of slide: 3 August 2016 The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. ©WHO All rights reserved. Introduced to date* (35 countries or 97%) Formal commitment to introduce in August 2016 (1 country or 3%) Not applicable / not available / not Tier 1 or 2 countries Since January 2013, the following Tier 1 and 2 countries have introduced IPV: The Philippines (October 2014), China (December 2014), Nigeria (February 2015), DR Congo (April 2015), Madagascar (May 2015), Cameroon, Niger and Pakistan (July 2015); Benin, Chad and Papua New Guinea (August 2015); Afghanistan and CAR (September 2015); Lao People's Democratic Republic (October 2015); Guinea, India, Mauritania, Mozambique, Somalia & Yemen (November 2015); Cambodia, Dominican Rep., Ethiopia, Gabon, Kenya, Myanmar & S. Sudan (December 2015); Haiti & Iraq (January 2016); Azerbaijan, Bolivia & Timor-Leste (February 2016); Mali (March 2016); Congo & Uganda (April 2016); Indonesia (July 2016)

7 |7 | Middle Income Countries using IPV vaccine to date and formal decision to introduce Data source: WHO/IVB Database, as of 03 August 2016 based on 104 middle income countries (MIC) as per last World Bank classification Map production Immunization Vaccines and Biologicals (IVB), World Health Organization Date of slide: 3 August 2016 The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. ©WHO All rights reserved. Since January 2013, the following MIC have introduced IPV: Kazakhstan (July 2013); Peru (July 2013); Libya (March 2014); Albania (May 2014); Panama (July 2014); Tunisia (September 2014); Philippines (October 2014); China (December 2014); Senegal (January 2015); Serbia (January 2015); Colombia (February 2015); Maldives (March 2015) and Cote d'Ivoire, Kiribati, Morocco, St Vincent and the Grenadines & Sudan (June 2015); Bhutan, Cameroon, Pakistan & Sri Lanka (July 2015); Papua New Guinea & the former Yugoslav Rep. of Macedonia (August 2015); Dominica, Guyana, Iran, Jamaica & Solomon Islands (September 2015); Lao People's Democratic Rep & Samoa (October 2015); Botswana, India, Mauritania, Mauritius, Namibia, Nicaragua, St Lucia, Tuvalu, Vanuatu & Yemen (November 2015); Algeria, Belize, Dominican Rep, Ecuador, Fiji, Gabon, Georgia, Honduras, Kenya, Myanmar, Paraguay, Thailand & Tonga (December 2015); Cuba, El Salvador, Iraq & Guatemala (January 2016); Azerbaijan, Bolivia & Timor-Leste (February 2016); Congo, Djibouti, Lesotho & Sao Tome & P. (April 2016); Armenia, Indonesia & Swaziland (July 2016) Introduced to date (91 countries or 87.5%) Not applicable / Not available / Not introduced / Non MIC Formal commitment to introduce in (13 countries or 12.5%)

8 |8 | Overview of Global birth cohort by IPV status/tier (100% = million births in 2016) * Partial Introduction Data source: WHO/IVB Database, as of 03 August 2016 and United Nations, Department of Economic and Social Affairs, Population Division (2015). World Population Prospects: The 2015 Revision

9 |9 | bOPV registration status for routine immunization Data source: WHO/IVB Database, as of 03 August 2016 Map production Immunization Vaccines and Biologicals (IVB), World Health Organization Date of slide: 3 August 2016 The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. ©WHO All rights reserved. Approval for use (143 countries) Review in progress (1 country – Mexico) Not applicable (switch area territories) Not available/ non switch countries