From: Hepatitis B Virus Strains with Mutations in the Core Promoter in Patients with Fulminant Hepatitis Ann Intern Med. 1995;122(4):241-248. doi:10.7326/0003-4819-122-4-199502150-00001.

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From: Hepatitis B Virus Strains with Mutations in the Core Promoter in Patients with Fulminant Hepatitis Ann Intern Med. 1995;122(4):241-248. doi:10.7326/0003-4819-122-4-199502150-00001 Figure Legend: A map of the X and precore-core genes and the fragment of hepatitis B virus (HBV) DNA sequenced.The initiation sites of two 3.5-kilobase messenger RNAs (mRNA) are indicated on the top. Boxes below represent liver-specific enhancer II, the basic core promoter, and a regulatory sequence located upstream of them. Positions of direct repeats (DR) are also shown. Sequences of HBV DNA amplified by the first or second round of polymerase chain reaction (PCR) are indicated at the bottom. nt = nucleotide. Date of download: 9/19/2016 Copyright © American College of Physicians. All rights reserved.

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