MiRNA-130a regulates C/EBP-ε expression during granulopoiesis by Maria T. Larsen, Mattias Häger, Andreas Glenthøj, Fazila Asmar, Stine N. Clemmensen, Helena.

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miRNA-130a regulates C/EBP-ε expression during granulopoiesis by Maria T. Larsen, Mattias Häger, Andreas Glenthøj, Fazila Asmar, Stine N. Clemmensen, Helena Mora-Jensen, Niels Borregaard, and Jack B. Cowland Blood Volume 123(7): February 13, 2014 ©2014 by American Society of Hematology

Expression of miR-130a and C/EBP-ε during human granulopoiesis. Maria T. Larsen et al. Blood 2014;123: ©2014 by American Society of Hematology

The miR-130a and C/EBP-ε expression in ATRA-induced MPRO cells. Maria T. Larsen et al. Blood 2014;123: ©2014 by American Society of Hematology

Target verification of miR-130a in C/EBP-ε 3 ʹ -UTR. Maria T. Larsen et al. Blood 2014;123: ©2014 by American Society of Hematology

The miR-130a affects cell growth and expression of mRNAs encoding specific granule protein. Maria T. Larsen et al. Blood 2014;123: ©2014 by American Society of Hematology

Expressing a C/EBP-ε mRNA unaffected by miR-130a partially restores the phenotype of the pEGP-miR-130a clone. Maria T. Larsen et al. Blood 2014;123: ©2014 by American Society of Hematology

MPRO cells overexpressing miR-130a resists ATRA-induced differentiation. Maria T. Larsen et al. Blood 2014;123: ©2014 by American Society of Hematology

Regulation of C/EBP-ε by miR-130a in human granulocytic precursors. Maria T. Larsen et al. Blood 2014;123: ©2014 by American Society of Hematology