Hippocampus Cerebral cortex

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Hippocampus Cerebral cortex   Table S1 KA-induced editing of AMPA/KA glutamate receptor subunits in the hippocampus and cortex of COX-2+/+ and COX-2-/- mice. Editing sites COX-2+/+ vehicle COX-2+/+ KA COX-2-/- vehicle COX-2-/- KA Hippocampus GluR2 R/G flip isoform 57.9 ± 1.0 56.6 ± 1.0 61.8 ± 3.4 61.0 ± 0.9 GluR2 R/G flop isoform 37.7 ± 1.1 38.4 ± 2.4 37.7 ± 1.5 40.7 ± 1.8 GluR5 Q/R 65.4 ± 1.1 65.7 ± 3.9 68.7 ± 2.0 68.0 ± 2.0 GluR6 I/V 79.0 ± 1.4 79.2 ± 1.5 75.6 ± 2.3 78.3 ± 1.3 GluR6 Y/C 89.8 ± 0.3 88.9 ± 0.8 87.5 ± 2.0 86.8 ± 2.2 GluR6 Q/R 89.2 ± 2.1 89.2 ± 2.2 91.7 ± 1.9 86.9 ± 2.0 Cerebral cortex 64.6 ± 5.5 68.2 ± 3.9 67.3 ± 3.0 65.5 ± 4.9 54.8 ± 1.4 55.3 ± 4.0 53.1 ± 3.6 52.6 ± 2.7 GluR4 R/G flip isoform 52.3 ± 2.8 54.9 ± 2.8 54.8 ± 1.8 52.2 ± 7.2 GluR4 R/G flop isoform 78.1 ± 0.9 81.4 ± 2.6 81.0 ± 2.7 81.1 ± 1.8 69.9 ± 1.8 73.4 ± 2.3 72.6 ± 2.1 70.3 ± 3.3 Data are Means ± SEM expressed as % editing level compared to their controls. Statistical analysis was performed with Student’s test.