Date of download: 11/12/2016 From: Association Between Efavirenz as Initial Therapy for HIV-1 Infection and Increased Risk for Suicidal Ideation or Attempted.

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Date of download: 11/12/2016 From: Association Between Efavirenz as Initial Therapy for HIV-1 Infection and Increased Risk for Suicidal Ideation or Attempted or Completed SuicideAn Analysis of Trial DataAn Analysis of Trial Data Ann Intern Med. 2014;161(1):1-10. doi: /M Cumulative incidence of suicidality and nonsuicide death. Cumulative incidence of suicidal ideation or attempted or completed suicide (suicidality) is presented on the left, and cumulative incidence of death attributed to causes other than reported suicide (competing risk) is presented on the right. Gray test was stratified by study. DSMB = data safety monitoring board; EFV = efavirenz; ITT = intention-to-treat. A. Follow-up was censored after DSMB recommendations pertaining to the EFV comparisons. B. The ITT approach, including follow-up from randomization to last on-study contact. Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

Date of download: 11/12/2016 From: Association Between Efavirenz as Initial Therapy for HIV-1 Infection and Increased Risk for Suicidal Ideation or Attempted or Completed SuicideAn Analysis of Trial DataAn Analysis of Trial Data Ann Intern Med. 2014;161(1):1-10. doi: /M Association between efavirenz and the hazard of suicidality. Univariate estimated hazard ratios were quantified from a Cox model with a Wald CI and P value, stratified by study, and are plotted on a logarithm scale. DSMB = data safety monitoring board; EFV = efavirenz; IR = incidence rate; ITT = intention-to-treat; PY = person-year. A. Follow-up was censored after DSMB recommendations pertaining to the EFV comparisons. B. The ITT approach, including follow-up from randomization to last on-study contact. * P value for EFV association; P values for interaction with EFV are presented for study and region. Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

Date of download: 11/12/2016 From: Association Between Efavirenz as Initial Therapy for HIV-1 Infection and Increased Risk for Suicidal Ideation or Attempted or Completed SuicideAn Analysis of Trial DataAn Analysis of Trial Data Ann Intern Med. 2014;161(1):1-10. doi: /M Cumulative incidence of attempted or completed suicide and nonsuicide death. Cumulative incidence of attempted or completed suicide is presented on the left, and cumulative incidence of death attributed to causes other than reported suicide (competing risk) is presented on the right. Gray test was stratified by study. DSMB = data safety monitoring board; EFV = efavirenz; ITT = intention-to-treat. A. Follow-up was censored after DSMB recommendations pertaining to the EFV comparisons. B. The ITT approach, including follow-up from randomization to last on-study contact. Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

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