Fate Mapping → Lineage tracing is the identification of all progeny of a single cell. Although its origins date back to developmental biology of invertebrates in the 19th century, lineage tracing is now an essential tool for studying stem cell properties in adult mammalian tissues. → Embryonic induction is an interaction between one (inducing) tissue and another (responding) tissue, as a result of which the responding tissue undergoes a change in its direction of differentiation. Within the field of developmental biology one goal is to understand how a particular cell (or embryo) develops into the final cell type (or organism), essentially how a cell's fate is determined. → In developmental biology, fate mapping is a method of understanding the embryonic origin of various tissues in the adult organism by establishing the correspondence between individual cells (or groups of cells) at one stage of development, and their progeny at later stages of development. When carried out at single-cell resolution, this process is termed cell lineage tracing.

Example of Fate Mapping Example of a fate map is that of Drosophila melanogaster.  This fly is known for having comparable larval and adult body segmentation regulated by a series of genetic mechanisms.  The fate map of D. melanogaster can be seen in many developmental biology texts.  Along with the production of a fate map, scientists have also been able to produce a map of developmental potential for the fruit fly.  The fate map of this organism has been a key factor in determining the complex genetic network used by the fruit fly.  Studies of how the fates of each segment are determined have resulted in the discovery of novel genes such as gurken, which determine axis formation in Drosophila. By vital staining of the surface of the developing fly egg or early embryo, it can be shown that particularly regions are always associated with particular structures in the adult fly.

3 germ layers formation of chick embryo

A comparison of early vertebrate embryos reveal similar patterns of development.

Fate map with transgenic DNA

Xenopus laevis The African clawed frog (Xenopus laevis, also known as the xenopus, African clawed toad, African claw-toed frog or the platanna) is a species of African aquatic frog of the Pipidae family. Its name is derived from the three short claws on each hind foot, which it uses to tear apart its food. The word Xenopus means "strange foot" and laevis means "smooth". Blastulation Gastrulation

Fate mapping using a fluorescent dye

Fate maps of vertebrates at the early gastrula stage

Homologies of structure among human arm,seal forelimb,bird wing,and bat wing

Intersectional genetic fate mapping strategy distinguishes r1(En1cre)-derived from non-r1-derived norepinephrine neurons.

Larval stages reveal common ancestry of two crustacean arthropods

Zebra fate map can be determined by early gastrulation