Linh Le, CEO linh@flextrapower.com Graphene Wearable Sensor for Health Applications Linh Le, CEO linh@flextrapower.com

30+ million diabetics in the US, ~300+ million in world 25% will experience a diabetic foot ulcer Diabetic neuropathy: patients can’t feel their feet Untreated ulcers become infected and gangrenous 200 amputations per day in the US ($70,434 each) 86% of all foot amputations in US are preceded by an ulcer Direct costs of ulcers approaches $15B in the US

How do temperature and health correlate? Thermal imaging can show high risk areas… but only at discrete times when the patient remembers to measure the temperature of their feet High risk areas Temperature is an indicator of underlying physiological processes taking place in the body. Normal metabolic functions blend together to produce an average body temperature in the human of approximately 37 degrees Centigrade. (advance to picture) But when there is an injury, or infection, physiological processes increase the amount of heat, which can be used as a signal of underlying medical need. Here we have a thermal image of a patient’s feet. Imagining can show high risk areas for damage to the feet. BUT, these data can only be collected Discrete foot temperature increases predict skin ulceration within one week

Innovative Data Collection Platform: Graphene Inkjet-Printed Sensors Single atomic sheet of carbon Electrically superconductive Near-perfect thermal conductor 200x stronger than steel Transparent Light Flexible Graphene is….. amazing! Inkjet-Printed Graphene Sensors can detect: Temperature Neural activity (EEG) Heart activity (ECG) Respiration Muscle activity (EMG)

Solution: Insole Sensors Array

Dr. Malcolm Nason, VP of R&D Management Team Linh Le, Founder and CEO PhD: Stevens Institute of Technology MS: Columbia University Co-inventor of five patent applications relating to his thesis work. Selected for “Entrepreneur Lab” program sponsored by NYCEDC. Multiple wins and finalist finishes in pitch competitions such as Google Solve for X and NJTech Meetup. New York Next Top Makers Fellow. Dr. Malcolm Nason, VP of R&D PhD: University of Chicago PostDoc: Columbia University MBA: Penn State University Deep experience in thermoregulatory physiology NARSAD award: Sydney Baer Jr Investigator Co-founded a diagnostics company, founding team for 2 other device firms Experienced in customer development, business development, product-market fit and strategic initiatives.

Our Asks? Regulatory and Compliance Consultant Lead FDA conversation Assist with filing Class I/II/III designation Advise experiment protocol for clinical trial data