Innovation Project Title Duke Institute for Health Innovation Innovation Project Title The following slides serve as a guidepost to constructing your pitch. Total number of slides should not exceed 5. **Delete this text box before submitting your pitch.** Your Name Team members Oct 2016

Project & Problem What is your idea? What is the pain point or unmet need that it addresses? Provide evidence for the need using data or an example. What stage of development is the innovation currently in? Has it received prior funding/investment? Why is your project the solution to this problem and how is it innovative? Duke Institute for Health Innovation (DIHI) A brief introduction: The Duke Institute for Health Innovation (DIHI), catalyzes innovation in health and healthcare at Duke University and Duke Health through its collaboration platform for sourcing and curating real-world health care problems and incubating innovative solutions to create real impact for patients and healthcare systems. DIHI focuses on driving a culture and ecosystem for innovation through engagement and projects in 4 innovation domains: (1) implementation and health delivery science, (2) health technology innovation, (3) workforce and leadership development, and (4) applied health policy. Please www. DIHI.org Through an annual RFA process DIHI sources Innovation pilots. The innovation process is aligned with DUHS and DUH strategy and planning process. Last year (RFA 2015) the thematic areas for innovation were Population Health and Analytics Reducing Medical Complications and Improving Care Transitions Primary Care innovations We received over 60 applications from across the university and through a rigorous process Duke Health leaders selected 9 projects for funding / piloting. Project details: WIRELESS TECH FOR COPD / CHF: Phase 1: Assessing data elements from digital technologies that are put into Epic to see what types of algorithms should be in place to accurately intervene on patients with CHF and COPD. Phase 2: Begin implementing these algorithms on a defined patient population of CHF and COPD to assess the alerts that are triggered within the EMR to intervene on patients more cost-effectively. MACHINE LEARNING for SURGICAL MODELS: The proposed machine learning - class discovery and predictive modeling techniques - provide the analytic tool set for understanding and managing post-operative outcomes by allowing practitioners to better understand variables they can and cannot control and providing a predictive and quantitative basis for optimizing surgical and post-surgical management. Unmanaged variability in post-operative outcomes leads to preventable morbidity and mortality for the patient, economic cost to society, with complications potentially multiplying the cost of a procedure by a factor of five. This project provides the means to operationalize insights via “predictive models as a service” within the Health System. DUKE CONNECTED CARE CKD: Synchronize Medicare claims data for the MSSP CKD population with clinical data from the DSR to support the development of predictive models to identify high-cost patients with accelerating kidney disease and multiple comorbid conditions, who would benefit from more intensive intervention. Novel visualizations would be developed as well to provide greater insight into the needs of the various segments of this heterogeneous population. SICKLE CELL DISEASE: The intervention is a provider-designed iOS-enabled mobile application used to improve health management for patients with SCD. The project aims to: Improve medication administration tracking and increase compliance Track symptoms and patient employed interventions and communicate with providers Education modules and provider feedback The patient group will be ~50 pediatric patients who are currently prescribed hydroxyurea (HU) and metrics will be medication adherence, hematologic values, patient disease knowledge, acceptability of the app, and improved quality of life and psychosocial variables.

The Plan & Metrics How much funding is your proposal seeking? Please state the amount. Provide a breakdown of your intended use of funds. What are the achievable outcomes and metrics of success at 1 year and 5 years? What is the plan after Innovation Jam investment? How will you generate ROI?