The Natural Broiler Digestive

the natural broiler digestive MODE OF ACTION Regulation of the guts’ microbial flora Stimulation of digestive enzymes Brovital: the natural broiler digestive

Supports compensatory growth Brovital effect weeks 1 2 3 4 5 6 7 8

Is added to the drinking water* The application: Is added to the drinking water* at 0,5 ltr./1000 ltr.one (1) week before the slaughtering date, during the first five days. * The quality of the drinking water could influence the final animal performance result.

Organic and non Organic acids Contains Natural plant extracts of specifically selected herbs, grown in the Mediterranean And... Organic and non Organic acids

What is known about herbs. They act Analgesic Anti-inflammatory Antiseptic Diuretic Flavouring Immunostimulant Stimulant Antioxidant Fungicide Insect repellant Anti-microbial

The Stimulating Effect Of Herbs Increasing enzyme production Source: Blumberger and Glatzel, 1963

Amylase Concentration In Poultry Duodenum stimulated by herbs

Families of molecules in essential oils Categorie Name Examples Importance in animals Terpene Hydrocarbons Monoterpenes(C10) Sesquiterpenes(C15) Diterpenes(C20) Triperpenes Citrus oils Chamonile Limone, pinene Some Oxygenated Compounds Phenols Aldehydes. (powerful aroma) Oxides (1.8-cinod Thyml,Carvacr.Eugen. Cinnemaldehyde Eucalypol Very Yes

What is the advantage of Brovital? Brovital is not an essential oil. Brovital contains Natural plant extracts ! Therefore Brovital contains all the natural essential elements for a good broiler performance in the last period

The herb extracts of Brovital in the drinking water reduce the impact of a coccidiosis infection in the bird. Source: Centre for animal science University of Leeds ( Ibrir, Greathead, Forbes)

Contains Acids

Organic acids Formic acid. Propionic acid. Acetic acid. Benzoeic acid. Citric acid. Sorbinc acid. Lactic acid Micro Organism. ( bacteria.) Molds, anti Microbial Bact. / molds / yeasts. Most effective against yeasts and bacteria. Palatability improver. Yeasts. Active in intestinal tract.

Hydrochloric acid (HCl),Sulpheric acid, Phosphoric acid. Anorganic acids Hydrochloric acid (HCl),Sulpheric acid, Phosphoric acid. Splits in an./cat. lowers pH. Organic acids ( Carbon groups) Ph reducing,Antimicrobial,conservation. Formic acid,Citric acid,Lactic acid,benzoic acid,buteric acid etc. Enter in non dissociated form cells. pH(pKa value=dissociation constant) value sensitive < pKvalue the stronger the acid > pH effect in the enviroment.

3 4 5 6 Fosforic acid 87 98 100 Fumaric acid 49 99 Citric acid 47 81 % Dissociation at pH 3 4 5 6 Fosforic acid 87 98 100 Fumaric acid 49 99 Citric acid 47 81 Formic acid 15 64 95 Propionic acid 2 12 58 93

Duration of transit time and pH in various GIT components Table shows pH and mean duration fof transit times, mash feed, after ad lib feeding during six weeks Gastrointestinal tract compartment Transit time Minutes pH Crop 50 5.5 Gizzard 90 2.5 - 3.5 Duodenum 5-8 5 - 6 Jejenum 20-30 6.5 - 7 Ileum 50-70 7 - 7.5 Rectum 25 8 Source: Dr HC Indresh

Dependent of pH and type of acid dissociation: H+ + anion- example: H3PO4 CH3COOH H+ + H2PO4- H+ + CH3COO-

Anti Microbial Activity R-COOH H+ RCOO- Cytoplasm Cell Wall

1. pH decrease Action and acid activity Lower pH => more H+ ions => more dissociation Depends of pH and type of acid

2. Antimicrobial activity * Absorption of acids (non-dissociated form) by bacteria and fungi * Acid dissociates in cell = H+ * pH in cell decreases and bacteria dies Depends of pH and type of acid

Strong acids --> pH decrease in stomach/feed and water e.g. fosforic acid, citric acid,... Non-dissociated acids--> prevention development of pathogens (anti microbial activity ) e.g. propionic acid, formic acid

Why ? Brovital contributes to a healthy broiler intestinal Micro flora. Supports the broiler genetical potential. Improves the broilers weight gain in the last days of life. Supports the broilers compensatory growth. Stimulates broilers enzyme secretion. Is added in the drinkingwater. Cleans the drinking system Gives an excellent cost benefit. Reduces ammonia in the litter. Therefore supports dry litter. Acts as an antioxydant. Already several Million broilers use BROVITAL!

The Benefit Trials under practical conditions show an average growth benefit, depending on the quality of the farm management, of 70-120 gr/bird at the end of the growing cycle. ..... and this without extra feed intake !

Therefore Brovital contains also acids