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Presentation transcript:

High School Presentation Jeans for Genes Day High School Presentation

What is Jeans for Genes Day? Section: one What is Jeans for Genes Day?

What is Jeans for Genes Day? Jeans for Genes Day raises much needed funds for Children’s Medical Research Institute (CMRI). It’s easy and fun to get involved: Simply swap your uniform for a pair of jeans and make a gold coin donation Hold a fundraising event, such as a bake sale or sporting challenge

What does CMRI do? Children’s Medical Research Institute conducts the ‘basic’ research that allows us to understand the fundamental causes of a range of disorders, such as cancer and epilepsy. This crucial foundation is needed if we are to find ways to treat or prevent these diseases. We are also dedicated to going beyond basic research, by translating the discoveries made in the laboratory into new treatments for patients through our gene therapy and drug discovery programs.

GENETICS: why we are the way we are There are lots of different things that make you ‘you’ and many are determined by your genes….

We all begin as 1 cell

Bodies are made of Cells

Cells have a Nucleus The nucleus contains Chromosomes Chromosomes are made of DNA

How DNA is packaged in chromosomes:

2.5 m One cell has 2.5m of DNA!!! 1.96 m 1.78 m 1.64 m 1.63 m 1.53 m

Humans have 46 chromosomes (23 pairs) female male sperm = egg = X , Y X , X

DNA is needed for Information Transfer

23 chromosomes from the egg and 23 from the sperm combine to make a human

To do this, cells need to divide…

…and DNA needs to replicate – this can lead to mistakes (or mutations) in genes G-C A-T

One small mistake can cause a genetic disease Ginger Pudding 200 gms flour 200gms sugar 2 eggs 125 gms butter 1 tspn ginger Ginger Pudding 200 gms flour 200gms sugar 2 eggs 125 gms butter 1 tspn finger A rare mutation gave Jacqui metatropic dysplasia. This disease interfered with her bone growth, so she has severe curvature of the spine, pigeon chest and problems with her joints that will affect her the rest of her life.

You can help CMRI find treatments for genetic diseases You can help CMRI find treatments for genetic diseases. Your donation makes a BIG difference!

Thanks for participating in Jeans for Genes Day!! You are helping to create a healthier, brighter future for children everywhere