Acute Pyelonephritis 姜岱山.

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Presentation transcript:

Acute Pyelonephritis 姜岱山

Introduction www.themegallery.com Last summer holiday one of my friends told me that she was ill. And she had been on a drip for 7 days. What’s wrong with her? She told me she got acute pyelonephritis. Company Logo

Main Contents 1. What is APN 2. Etiology and pathogenesis 3. Features www.themegallery.com 1. What is APN 2. Etiology and pathogenesis 3. Features 4. Complications 5. Clinical 6. Prognosis Company Logo

What is acute pyelonephritis www.themegallery.com APN is a common suppurative inflammation of kidney and the renal pelvis. APN is caused by bacterial infection, principally E-coil. APN is an important manifestation of urinary tract infection. Company Logo

Etiology and pathogenesis www.themegallery.com Infection ①hematogenous spread ②ascending infection Urinary tract obstruction APN Company Logo

Suppurative inflammation Features www.themegallery.com APN Gross patterns discrete, yellowish, raised abscesses are grossly apparent on the renal surface Histological tubular necrosis, and neutrophilic casts, and abscesses formation patchy interstitial Suppurative inflammation Features Company Logo

Histological www.themegallery.com Company Logo

macrograph www.themegallery.com Company Logo

Acute necrotizing paplillitis Perinephric abscesses Complications www.themegallery.com Acute pyelonephritis Three complications Acute necrotizing paplillitis Perinephric abscesses pyonephrosis Company Logo

pyonephrosis www.themegallery.com Company Logo

Clinical www.themegallery.com 1 The onset is usually sudden, with pain at costovertebral angle. 2 Systemic evidence of infection such as fever and malaise. 3 Frequency, urgency, urine pain. Pyuria, bacteriuria, albuminuria, cylindruria, hematuria Company Logo

chronic pyelonephritis Prognosis www.themegallery.com recovery(most) active treatment treatment is delayed. chronic pyelonephritis Company Logo

Thank You !