Screening Diagnostic Tests for PE Type of Screening Tests General evaluation MRI, EEG, CMP, CBC, ophthalmologic exam, audiology Autoimmune disorder ESR, ANA, complement levels Autonomic disorder Histamine skin test, sweat testing Endocrinopathy TSH/T4, ACTH, cortisol Genetic disorder SNP microarray, MECP2 testing Infection CSF cell count, glucose, protein, CSF bacterial/viral cultures, CSF HIV/HSV PCR, CSF fungal antigens, CSF prion proteins, CSF viral antibodies Intoxication Lead, urine toxicology Metabolic disorder SAA, lactate, pyruvate, ammonia, carnitine, ACP, cholesterol/lipid panel, VLCFA, lysosomal enzyme analysis, lymphocyte vacuolization, UOA, porphyrins, CSF lactate/AA/NT metabolites Neoplastic disorder CSF cytologic analysis, paraneoplastic antibodies Nutritional disorder Niacin, thiamine, pyridoxine, cobalamin, Vit D, homocysteine, methylmalonic acid