Volume 133, Issue 4, Pages 1093-1098 (October 2007) Development of Colorectal Tumors in Colonoscopic Surveillance in Lynch Syndrome  Jukka–Pekka Mecklin, Markku Aarnio, Esa Läärä, Matti V. Kairaluoma, Kirsi Pylvänäinen, Päivi Peltomäki, Lauri A. Aaltonen, Heikki J. Järvinen  Gastroenterology  Volume 133, Issue 4, Pages 1093-1098 (October 2007) DOI: 10.1053/j.gastro.2007.08.019 Copyright © 2007 AGA Institute Terms and Conditions

Figure 1 Lexis-diagrams showing the individual prevalent (found at the first colonoscopy, marked by bullets) and incident cases (found during the follow-up period, marked by squares) of adenoma (left panel) and carcinoma (right panel) as well as the individual follow-up times (gray lines) from the first colonoscopy until an incident case is found, by calendar time and age. Gastroenterology 2007 133, 1093-1098DOI: (10.1053/j.gastro.2007.08.019) Copyright © 2007 AGA Institute Terms and Conditions

Figure 2 Kaplan–Meier curves showing the estimated cumulative risks of developing adenoma (A, B), carcinoma (C, D), and either tumor in male (E) and female (F) Lynch syndrome mutation carriers by age. The solid lines describe the point estimates, and the dashed lines show the 95% confidence limits of the risks at each age. Gastroenterology 2007 133, 1093-1098DOI: (10.1053/j.gastro.2007.08.019) Copyright © 2007 AGA Institute Terms and Conditions