Figure 5. Tbr2 and Tbr2-GFP expression in P7 cortex

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Figure 5. Tbr2 and Tbr2-GFP expression in P7 cortex Figure 5. Tbr2 and Tbr2-GFP expression in P7 cortex. (A) Double labeling for Tbr2 (red) and Tbr2-GFP (green) showed double-labeled cells in the DG, the pPV adjacent to hippocampus (Nakatomi et al. 2002), the SVZ, and the RMS. Insets show selected zones at higher magnification. Parasagittal. (B–C) Double labeling for doublecortin (red) and Tbr2-GFP (green) in neocortex adjacent to SVZ confirmed neuronal differentiation. Panel (C) shows higher magnification of a cell with migratory morphology from (B). (D) Double labeling for GFAP (red) and Tbr2-GFP (green) in the cerebral cortex showed no astrocytic differentiation. (E) Double labeling for O4 (red) and Tbr2-GFP (green) showed no oligodendroglial differentiation. Scale bars: (A) 500 μm (250 μm for insets); (B, D–E) 20 μm (in B); (C) 10 μm (in B). From: Intermediate Neuronal Progenitors (Basal Progenitors) Produce Pyramidal–Projection Neurons for All Layers of Cerebral Cortex Cereb Cortex. 2009;19(10):2439-2450. doi:10.1093/cercor/bhn260 Cereb Cortex | Published by Oxford University Press 2009. 1