Harry Lampiris, MD, Moderator Chief, ID Section, Medical Service, SFVAMC Professor of Clinical Medicine, UCSF

The following CME Committee members, planners, and speakers have disclosed that they have no conflicts of interest or relevant financial relationships with commercial interests: CME Committee members: Sharon Adler, MD; David Couch; Kathleen Clanon, MD; Johanna Rosenthal, MPH; Pat Blackburn, MPH; Richard Fischer, MD Planning Committee members: Amanda Newstetter, Claire Rappoport, Jessica Price, and Harry Lampiris Speakers: Harry Lampiris MD, Susa Coffey MD, Jennifer Price MD PhD, and Hyman Scott MD MPH bayareaaetc.org

Learning objectives: 1. Identify the current science research on the pathogenesis of HIV and explain the key concepts around advances toward a Cure 2. Explain key findings in HIV clinical trials, and how this translates to new HIV and HCV treatment strategies 3. Describe the most current data around HIV infection, transmission, treatment, and linkage to and retention in care in populations worldwide. Identify ways to use this data in program planning bayareaaetc.org

CROI in Seattle: Feb 13 – 16, 2017 2 rain free days!!! 4200 participants, 1057 abstracts, 153 oral abstracts and symposia Focus on new agents, ARV strategies, HCV DAA rollout, PrEP implementation, ARV rollout worldwide, cure research 90/90/90 sometimes achieved, but increasing ARV resistance in developing world due to lack of viral load testing

We can’t cover everything, but… Prednisone therapy reduces risk of TB IRIS in RCT (81LB) Case report of DOL resistance in ARV naïve patient reported (500LB) No need to obtain baseline integrase resistance testing (493) First line integrase inhibitor regimen use associated with increased risk of IRIS (731, 732) TLR-7 agonist induced viral remission in two of four rhesus macaques (338LB)

Our speakers Hyman Scott, MD, MPH Jennifer Price, MD, PhD Medical Director, Clinical Research, Bridge HIV, SFDPH Attending Physician, ZSFG Ward 86 Clinic Assistant Professor of Medicine, Division of HIV, ID Global Health, UCSF Jennifer Price, MD, PhD Transplant Hepatologist, UCSF Medical Center Assistant Professor of Medicine, GI Division, UCSF Susa Coffey, MD Professor of Medicine, Division of HIV, ID, Global Health, UCSF Editor in Chief, UCSF Center for AIDS Information and HIV InSite Medical Editor, AETC National Resource Center

Acknowledgements Amanda Newstetter and Jessica Price, SF AETC Claire Rappoport, Community Consortium Gilead Sciences Our speakers and audience Please complete your evaluation to receive CME credit at: http://tinyurl.com/CROI2017 Thank you for supporting this event! Please remove all trash from room!!

The Pacific AIDS Education & Training Center HIV Learning Network (HIVLN) is a free telehealth HIV mentoring, training and consultation program for HIV clinical care teams and individual clinicians in Arizona, California, Hawai'i, and Nevada. HIVLN provides bimonthly live, on-line mentoring and consultation sessions on the second and fourth Thursdays of the month from 12:00·1 :00 pm PST.