Hypoxia imaging with [18F]HX4 PET in NSCLC patients: Defining optimal imaging parameters Catharina M.L. Zegers, Wouter van Elmpt, Roel Wierts, Bart Reymen,

Slides:

Advertisements

Similar presentations

2015 Alzheimer's disease facts and figures Alzheimer's & Dementia: The Journal of the Alzheimer's Association Volume 11, Issue 3, Pages (March.

Advertisements

Port-site recurrence in a patient undergoing robotic hysterectomy and lymph node dissection for endometrioid adenocarcinoma of the uterus Ioannis Alagkiozidis,

Feifei Teng, Christina I. Tsien, Theodore S. Lawrence, Yue Cao

Correlation of 18F-FDG Avid Volumes on Pre–Radiation Therapy and Post–Radiation Therapy FDG PET Scans in Recurrent Lung Cancer Nadya Shusharina, PhD,

Michalis Aristophanous, Yue Yong, Jeffrey T. Yap, Joseph H

Pre- and per-treatment 18F-FDG PET/CT parameters to predict recurrence and survival in cervical cancer Julie Leseur, Geoffrey Roman-Jimenez, Anne Devillers,

Volume 75, Issue 1, Pages (January 2012)

Acute symptoms during the course of head and neck radiotherapy or chemoradiation are strong predictors of late dysphagia Hans Paul van der Laan, Hendrik.

Comparison of Nodal Risk Formula and MR Lymphography for Predicting Lymph Node Involvement in Prostate Cancer Willem M.L.L.G. Deserno, M.D., M.Sc., Oscar.

Individualized Positron Emission Tomography–Based Isotoxic Accelerated Radiation Therapy Is Cost-Effective Compared With Conventional Radiation Therapy:

Long-term follow-up of patients with locally advanced non-small cell lung cancer receiving concurrent hypofractionated chemoradiotherapy with or without.

Evaluation of 18F-FDG PET-CT for Differentiation of Pulmonary Pathology in an Approach of Outpatient Fast Track Assessment Tjeerd S. Aukema, MD, Renato.

Treatment of stage I NSCLC in elderly patients: A population-based matched-pair comparison of stereotactic radiotherapy versus surgery David Palma, Otto.

Impact of post operative intensity modulated radiotherapy on acute gastro-intestinal toxicity for patients with endometrial cancer: Results of the phase.

Is contrast enhancement required to visualize a known breast tumor in a pre-operative CT scan? Liesbeth J. Boersma, Bianca Hanbeukers, Carla Boetes,

Simultaneous positron emission tomography (PET) assessment of metabolism with 18F- fluoro-2-deoxy-d-glucose (FDG), proliferation with 18F-fluoro-thymidine.

Development of a multivariable normal tissue complication probability (NTCP) model for tube feeding dependence after curative radiotherapy/chemo-radiotherapy.

Swallowing sparing intensity modulated radiotherapy (SW-IMRT) in head and neck cancer: Clinical validation according to the model-based approach Miranda.

Reducing radiation dose and enhancing imaging quality of 4DCT for radiation therapy using iterative reconstruction algorithms George Noid, PhD, An Tai,

Effect of variations in atelectasis on tumor displacement during radiation therapy for locally advanced lung cancer Nathan Tennyson, MD, Elisabeth Weiss,

Esophageal adenocarcinoma five years after laparoscopic sleeve gastrectomy. A case report Fernando Gabriel Wright, Agustin Duro, Juan Rodolfo Medici,

Cardiac comorbidity is an independent risk factor for radiation-induced lung toxicity in lung cancer patients Georgi Nalbantov, Bas Kietselaer, Katrien.

Automated delineation of brain structures in patients undergoing radiotherapy for primary brain tumors: From atlas to dose–volume histograms Manuel Conson,

PET, CT, and MRI with Combidex for mediastinal staging in non-small cell lung carcinoma Kemp H Kernstine, MD, PhD, William Stanford, MD, Brian F Mullan,

Volume 54, Issue 4, Pages (October 2008)

Dosimetric Consequences of 3D Versus 4D PET/CT for Target Delineation of Lung Stereotactic Radiotherapy Shankar Siva, MBBS, FRANZCR, Brent Chesson, BAppSc.

Prognostic Significance of the Number of Lymph Nodes Removed at Lobectomy in Stage IA Non-small Cell Lung Cancer Sai-Hong Ignatius Ou, MD, PhD, Jason.

Evaluation of diffusion weighted imaging for tumor delineation in head-and-neck radiotherapy by comparison with automatically segmented 18F-fluorodeoxyglucose.

Paraneoplastic Opsoclonus-Myoclonus Syndrome as a New and Single Manifestation of Relapsing Disease in a Patient with Small Cell Lung Cancer Ernest Nadal,

Resection of Mucinous Lung Adenocarcinoma Presenting with Intractable Bronchorrhea Motoshi Takao, MD, PhD, Takehiro Takagi, MD, Hitoshi Suzuki, MD, PhD,

Retrospective assessment of MRI-based volumetric changes of normal tissues in glioma patients following radio(chemo)therapy Andreas Gommlich, Felix Raschke,

Michiel van den Bosch, Michel Öllers, Bart Reymen, Wouter van Elmpt

Results of a Multicentric In Silico Clinical Trial (ROCOCO): Comparing Radiotherapy with Photons and Protons for Non-small Cell Lung Cancer Erik Roelofs,

Physics and Imaging in Radiation Oncology

Improving CT quality with optimized image parameters for radiation treatment planning and delivery guidance Guang-Pei Chen, George Noid, An Tai, Feng.

Robotic-assisted surgery in gynecologic oncology

FDG-PET and FDG-PET/CT for Diagnosing Infection in Patients with Multiple Vascular Bypass Grafts: A Report of Two Cases V.E. de Meijer, A.W.H. van de.

Esophageal Ultrasound-Controlled Fine Needle Aspiration for Staging of Mediastinal Lymph Nodes in Patients with Resectable Lung Cancer: Do We Always See.

Axillary radiotherapy for nodal lymphoma: What CTV expansion is required to account for absence of pre-chemotherapy treatment position FDG PET-CT? Robin.

Ilja F. Ciernik, Anja M. Greiss

Potentials and challenges of diffusion-weighted magnetic resonance imaging in radiotherapy Sara Leibfarth, René M. Winter, Heidi Lyng, Daniel Zips, Daniela.

Successful immunotherapy and irradiation in a HIV-positive patient with metastatic Merkel cell carcinoma Annett Linge, Ricarda Rauschenberg, Sophia Blum,

Long term safety and visibility of a novel liquid fiducial marker for use in image guided radiotherapy of non-small cell lung cancer Steen Riisgaard.

Diagnosis of Mediastinal Adenopathy—Real-Time Endobronchial Ultrasound Guided Needle Aspiration versus Mediastinoscopy Armin Ernst, MD, FCCP, Devanand.

Survival analysis Diagnostic Histopathology

Combined morphologic and metabolic pipeline for Positron emission tomography/computed tomography based radiotherapy response evaluation in locally advanced.

A Pragmatic Approach to the Diagnosis of Nodal Micrometastases in Early Stage Non- small Cell Lung Cancer Esther Herpel, MD, Thomas Muley, PhD, Thomas.

Cone-Beam CT-based position verification for oesophageal cancer: Evaluation of registration methods and anatomical changes during radiotherapy A. van.

The role of positron emission tomography for non-small cell lung cancer Albert J. Chang, MD, PhD, Farrokh Dehdashti, MD, Jeffrey D. Bradley, MD Practical.

Fast 4D cone-beam CT from 60 s acquisitions

Radiotherapy for isolated granulocytic sarcoma: Case report and review of literature Jose Antonio Dominguez Rullán, Eva Fernández Lizarbe, Belén Capuz,

A Patient With BRAF V600E Lung Adenocarcinoma Responding to Vemurafenib Oliver Gautschi, MD, Chantal Pauli, MD, Klaus Strobel, MD, Astrid Hirschmann,

Volume 4, Issue 5, Pages 2-3 (October 2006)

Clinical and radiobiological evaluation of a method for planning target volume generation dependent on organ-at-risk exclusions in magnetic resonance.

PD5-1-7: Time trends in nodal CT volume and nodal motion during radiotherapy for patients with stage III non-small cell lung cancer Geert Bosmans, Angela.

Uncertainty evaluation of image-based tumour control probability models in radiotherapy of prostate cancer using a visual analytic tool Oscar Casares-Magaz,

Sites of recurrent disease and prognostic factors in SCLC patients treated with radiochemotherapy Rebecca Bütof, Calogero Gumina, Chiara Valentini, Antje.

High Frequency of Radiation Pneumonitis in Patients with Locally Advanced Non-small Cell Lung Cancer Treated with Concurrent Radiotherapy and Gemcitabine.

Patterns of Locoregional Relapses in Patients with Contemporarily Staged Stage III-N2 NSCLC Treated with Induction Chemotherapy and Resection: Implications.

Correlation between FMISO-PET based hypoxia in the primary tumour and in lymph node metastases in locally advanced HNSCC patients Anna Bandurska-Luque,

International Thymic Malignancies Interest Group: A Way Forward

Prostate-specific membrane antigen positron emission tomography/computed tomography as a potential tool to assess and guide salivary gland irradiation

Recurrent Primary Synovial Sarcoma of the Chest Wall

Patterns of practice in palliative radiotherapy for bleeding tumours in the Netherlands; a survey study among radiation oncologists Jennifer Strijbos,

Radical Treatment of Non–Small-Cell Lung Cancer Patients with Synchronous Oligometastases: Long-Term Results of a Prospective Phase II Trial (Nct )

Technical Innovations and Patient Support in Radiation Oncology

Peter de Boer, Stefano Mandija, Anita M

Change in FES uptake in the tumor during fulvestrant treatment.

Probabilistic optimization of dose coverage in radiotherapy

Volumetric and dosimetric comparison of two delineation guidelines for the radiation treatment of laryngeal squamous cell carcinoma C. Bondue, S. Racadot,

Presentation transcript:

Hypoxia imaging with [18F]HX4 PET in NSCLC patients: Defining optimal imaging parameters Catharina M.L. Zegers, Wouter van Elmpt, Roel Wierts, Bart Reymen, Hoda Sharifi, Michel C. Öllers, Frank Hoebers, Esther G.C. Troost, Rinus Wanders, Angela van Baardwijk, Boudewijn Brans, Jonas Eriksson, Bert Windhorst, Felix M. Mottaghy, Dirk De Ruysscher, Philippe Lambin Radiotherapy and Oncology Volume 109, Issue 1, Pages 58-64 (October 2013) DOI: 10.1016/j.radonc.2013.08.031 Copyright © 2013 The Authors Terms and Conditions

Fig. 1 Example of two transversal slices of the [18F]HX4 CT/PET image of patient 14 at 2h and 4h p.i. showing the primary tumor (GTVprim) and involved lymph nodes (GTVln). Radiotherapy and Oncology 2013 109, 58-64DOI: (10.1016/j.radonc.2013.08.031) Copyright © 2013 The Authors Terms and Conditions

Fig. 2 TBRmax of the primary tumor (GTVprim) and involved lymph nodes (GTVln) of all patients. Radiotherapy and Oncology 2013 109, 58-64DOI: (10.1016/j.radonc.2013.08.031) Copyright © 2013 The Authors Terms and Conditions

Fig. 3 Example of patient 8. Left figure shows the 2h p.i. [18F]HX4 PET/CT that is rigidly registered to the 4h p.i. scan (middle). Visualized are the gross tumor volume (blue) and the hypoxic volume in the 4h p.i. scan and its corresponding high uptake volume in the 2h p.i. scan (red). The right figure shows the voxel-wise comparison between 2h and 4h p.i. within the gross tumor volume. Radiotherapy and Oncology 2013 109, 58-64DOI: (10.1016/j.radonc.2013.08.031) Copyright © 2013 The Authors Terms and Conditions

Fig. 4 Transversal [18F]HX4 PET slice of patient 4 at 4h p.i., reconstructed with the total acquisition of 30min or the first 20, 10 and 5min. Radiotherapy and Oncology 2013 109, 58-64DOI: (10.1016/j.radonc.2013.08.031) Copyright © 2013 The Authors Terms and Conditions