Live Volumetric Imaging (LVI)® Intracardiac Ultrasound Catheter

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Presentation transcript:

Live Volumetric Imaging (LVI)® Intracardiac Ultrasound Catheter David E. Dausch, PhD Senior Research Engineer Cardiovascular Innovations February 26, 2013 Copyright © 2013 RTI. All rights reserved.

I/we have no real or apparent conflicts of interest to report. David E. Dausch, PhD I/we have no real or apparent conflicts of interest to report.

Acknowledgements RTI International (Research Triangle Park, NC) Kristin Gilchrist, PhD, Research Scientist Jim Carlson, Senior Research Engineer Steve Hall, Process Engineer Duke University (Durham, NC) Olaf von Ramm, PhD, Thomas Lord Professor Biomedical Engineering John Castellucci, Senior Research Engineer

Live Volumetric Imaging (LVI) Technology Breakthrough ultrasound transducer platform enabling the first intracardiac catheter capable of true real-time 3D echo Full volume sector High volume frame rate Good resolution Deep penetration depth Volume echo image of porcine right ventricle Tricuspid valve RV Septum Imaging produced by Duke University

Animated illustration

Breakthrough Transducer Technology Piezoelectric Micromachined Ultrasound Transducer (pMUT) Real-time 3D imaging  Matrix array transducers Better transducer performance  MEMS flexural membrane elements Efficient manufacturing  Semiconductor batch processing signal cable pMUT array

LVI Performance Matching User Needs Technology LVI ICE Mechanical 4D ICE1 3D TEE2 Volume sector 60° x 60° (up to 80° x 80°) 60° x 90° (up to 90° x 90°) Scan depth 8-10 cm 6 cm >10 cm Frame rate 25-30 vol/s 6 vol/s 7-10 vol/s Resolution 1 mm (40 mm depth) good Transducer cost $ $$ $$$ Key: Best Sufficient Poor 1 Lee et al. (2010) Proc. IEEE IUS: 833 2 Faletra et al. (2012) Circ. J. 76:5

Demonstrated In vivo Intracardiac Imaging LVI prototypes fabricated Matrix phased array, 5 MHz 256 to 512 elements Side-looking Integrated signal cabling 14F diameter 90 cm working length Bi-directional steering Animal studies conducted Porcine model Femoral vein access to right atrium Laboratory 3D ultrasound scanner Duke biomedical engineering LVI cath

Real-time Right Heart Visualization B-mode TV 60ox60o Volume 10 cm depth 26 vol/s RA RV S Orthogonal B-modes Imaging produced by Duke University

Expected Benefits of LVI Real-time 3D views Spatial relationships, structural dynamics, en face views Depth perception and continuous views of targets No mental reconstruction or geometric assumptions ICE modality Targets viewed in near field with better resolution Imaging catheter in control of interventionalist Reduced fluoroscopic radiation dose Overcome disadvantages of TEE Limited views (probe maneuverability, anterior depth) Targets in far field (reduced resolution) Volume size, frame rate tradeoff Volume averaging, stitch artifacts General anesthesia and intubation

LVI … The Future of ICE? Revolutionary Ultrasound Transducer Platform Real-time 3D imaging  Matrix array transducers Better transducer performance  Smaller element size Efficient manufacturing  Semiconductor MEMS processing Miniaturization  Catheter packaging Real-time 3D Intracardiac Echo Full volume Deep penetration High volume frame rate Good resolution For more information: www.rti.org/lvi