Volume 58, Issue 5, Pages 655-668 (November 2010) Prognostic and Therapeutic Impact of the Histopathologic Definition of Parenchymal Epithelial Renal Tumors Vincenzo Ficarra, Matteo Brunelli, Liang Cheng, Ziya Kirkali, Antonio Lopez-Beltran, Guido Martignoni, Rodolfo Montironi, Giacomo Novara, Hein Van Poppel European Urology Volume 58, Issue 5, Pages 655-668 (November 2010) DOI: 10.1016/j.eururo.2010.08.001 Copyright © 2010 European Association of Urology Terms and Conditions
Fig. 1 Renal cell neoplasms (major histotypes): immunohistochemical and fluorescent in situ hybridization analysis. (A) Clear cell renal cell carcinoma (hematoxylin and eosin [H&E]); (B) immunoreactivity for CD10 and (C) loss of 3p (orange: CEP3; green: 3p); (D) papillary renal cell carcinoma (H&E); (E) immunoreactivity for CK7 and (F) gains of chromosomes 7 and 17 (orange CEP17; green CEP7); (G) chromophobe renal cell carcinoma (H&E), (H) immunoreactivity for parvalbumin and (I) loss of chromosome 6 (green: CEP 6); (J) renal oncocytoma (H&E), (K) immunoreactivity for S100A1, and (L) normal numerical complement of both chromosomes 2 and 6 (orange: CEP 2; green: CEP 6). European Urology 2010 58, 655-668DOI: (10.1016/j.eururo.2010.08.001) Copyright © 2010 European Association of Urology Terms and Conditions
Fig. 2 Recently described new entities: (A) clear cell papillary renal cell carcinoma; (B) renal cell carcinoma with prominent leiomyomatous proliferation; (C) tubulocystic renal cell carcinoma; (D) oncocytic papillary renal cell carcinoma. European Urology 2010 58, 655-668DOI: (10.1016/j.eururo.2010.08.001) Copyright © 2010 European Association of Urology Terms and Conditions