TVS Temperature Verification System (For BMS Distributors Only) All information within this presentation is subject to change. © 2017 Bio Molecular Systems Pty. Ltd. – All rights reserved

No Calibration Required Nothing to degrade Common block based cyclers use Peltier elements. Peltier’s age as does the heat sink compound that keeps them in thermal contact with the block and the heat sink below. Mic is a non-contact system. The rotor is not in contact with anything physical just the induction field. That's why nothing changes over time. Minimal sensor drift over time. Thermal sensor embedded in spinning rotor. Measures rotor temperature directly. Drift reported by manufacturer to be < 1.5% after 6000 h at 100°C 1 Temperature Verification System. For laboratories requiring certification of equipment. 1 Source: Phil Waterworth (2003) Reliability Studies on Betatherm Discrete Radial Insulated NTC Thermistor Components.

Temperature Verification System Mic TVS Temperature Verification System Assured System Performance Designed to meet the rigorous requirements of international quality standards, Mic TVS will verify the thermal accuracy of your Mic instrument. It uses a sensor permanently embedded in a tube so we know exactly what the temperature inside your tubes are. Each Mic TVS is calibrated in house on a system traceable to a NATA reference standard. Plug and Play The process is so simple anyone can do it! Built right into the Mic software is a wizard to guide you step by step through the process. Upon completion a report is generated which can be printed and stored for your documentation. The whole process is completed in less than 25 minutes. Calibration of TVS In addition we offer an annual calibration service for your Mic TVS so you can be sure your instruments are always performing at their best.

Comparative Validation Costs Company Product or Service Cost (USD) Notes Qiagen Rotor-Disc OTV $1,400 Light sensitive, short shelf life with maximum usage of 30 tests per rotor. Bio-Rad Thermal Validation Service $3,000 Onsite service. Technician needs to fly in. Thermo-Fisher On-site Temperature Verification Service $4,500 Has to be conducted as a complete maintenance package. Technician from Thermo-Fisher needs to fly in and it takes over a day to do. Cycler Test MTAS Calibration $600 Done through distributor. Distributor pays a licence fee for each test. Cycler Test captures all the data for each test. Setup is tedious and takes over an hour to complete.

Using the TVS Setup Verification Report Plug TVS unit into PC. Load sensor tubes into Mic. Follow the Wizard instructions. Completed in less than 25 min. Report provides a document of the verification.

TVS Options Provide as a service* Sell direct to end user Pick which option best suites you. Provide as a service* Recommended charge $500 - $700 USD Annual calibration of TVS unit $750 USD Sell direct to end user Recommended retail price of $6000 - $7000 USD OR *Upfront purchase of TVS from BMS is $5,000 USD

Specifications Specification Value Physical Dimensions   Dimensions W: 45 mm, L: 125 mm, H: 80 mm Weight 225 g Hardware Input USB Performance Temperature Accuracy ± 0.2oC Verification Temperatures 60 and 95oC Verification time 25 min (approx.) Operating Environment Temperature 22 – 28oC Relative Humidity 20 – 80% Ordering TVS REF MIC-TVS TVS Calibration Service REF MIC-TVSCAL sales@biomolecularsystems.com www.mic-qpcr.com