Current concept of chronic mountain sickness: pulmonary hypertension–related high- altitude heart disease Ri-Li Ge, MD, PhD, Gaowa Helun, BS Wilderness.

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Presentation transcript:

Current concept of chronic mountain sickness: pulmonary hypertension–related high- altitude heart disease Ri-Li Ge, MD, PhD, Gaowa Helun, BS Wilderness & Environmental Medicine Volume 12, Issue 3, Pages 190-194 (September 2001) DOI: 10.1580/1080-6032(2001)012[0190:CCOCMS]2.0.CO;2 Copyright © 2001 Wilderness Medical Society Terms and Conditions

Figure 1 Chest radiograph of a 4-year-old Han boy with high-altitude heart disease. He was born at 3400m. There is marked prominence of central pulmonary artery branches and enlargement of the right atrium and right ventricle. Data from Lin et al.14 Wilderness & Environmental Medicine 2001 12, 190-194DOI: (10.1580/1080-6032(2001)012[0190:CCOCMS]2.0.CO;2) Copyright © 2001 Wilderness Medical Society Terms and Conditions

Figure 2 Lung tissue of a 4-month-old boy who died of high-altitude heart disease. There is marked medial hypertrophy of the small pulmonary artery. Data from Li and Sui.11 Wilderness & Environmental Medicine 2001 12, 190-194DOI: (10.1580/1080-6032(2001)012[0190:CCOCMS]2.0.CO;2) Copyright © 2001 Wilderness Medical Society Terms and Conditions

Figure 3 Lung tissues of pika (A) and rat (B) kept at altitude. In pika, there is a very thin-walled pulmonary arteriole with a wall consisting of a single elastic lamina, while in the rat there is a thick muscular wall composed of thick smooth muscle sandwiched between inner and outer elastic lamina. Data from Ge et al.21 Wilderness & Environmental Medicine 2001 12, 190-194DOI: (10.1580/1080-6032(2001)012[0190:CCOCMS]2.0.CO;2) Copyright © 2001 Wilderness Medical Society Terms and Conditions