(1) Division and differentiation in human cells

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Key Area 1.1 – Division and Differentiation of Human Cells

Presentation transcript:

(1) Division and differentiation in human cells (F) Cancer Cells (A) Somatic cells Human Cells (E) Uses of stem cells (B) Differentiation in cells (D) Germline cells (C) Stem cells

Division and differentiation in human cells (F) Define how cancer develops in the body Define how a tumour can develop in the body State 2 characteristics of a tumour State the consequence of one of these features

Uncontrolled Cell Division Normal cell division Cancerous cell division Day 1 cells Day 2 Day 3 Day 4 Day 5 Cancer: Unregulated Cell Division - YouTube

They do not respond to normal regulatory signals that would instruct them to stop dividing when necessary. They lose the molecules on their surface that would normally hold them in place and can therefore be detached from their neighbours, causing the cells to spread (malignant tumour).

Differences between cancer and normal cells

What happens when cell division goes wrong? Cell division is very strictly controlled by genes. However, if the gene that controls cell division is incorrectly triggered, then cell division can occur uncontrollably. This means cells will continue to grow and grow and grow. This is cancer. Cancer cells divide excessively to produce a mass of abnormal cells (called a tumour). These cells do not respond to regulatory signals and May fail to attach to each other. If the cancer cells fail to attach to each other they can spread through the body to form secondary tumours.

Cancer – Summary video (5 minutes) Cancer: from a healthy cell to a cancer cell